Cerebral hypometabolism in a pediatric patient with clinically resolved posterior reversible encephalopathy syndrome.

A 4-year-old boy with Nuclear factor-kappa B Essential Modulator deficiency syndrome presented with encephalopathy post haematopoietic stem cell transplantation. MRI demonstrated T2/FLAIR-hyperintensities in the posterior cerebral cortex concerning for posterior reversible encephalopathy syndrome. Clinical improvement was appreciated following withdrawal of the suspected offending pharmacological agent (Cyclosporine).

Educational experiences of U.S. children during the 2020-2021 school year in the context of the COVID-19 pandemic.

The coronavirus disease 2019 (COVID-19) pandemic is a historic event impacting children around the globe. Prior research on the educational experiences of children during the COVID-19 pandemic focused almost exclusively on spring 2020. This article extends this literature past the initial shock of spring 2020, capturing the first full school year (2020-2021) during the COVID-19 pandemic.

Daily general discrimination predicts changes in trait negative affectivity: A 30-year cohort longitudinal study using a random-intercept cross-lagged panel model.

Objective: Increasing evidence indicates discrimination is an emerging risk factor for reducing psychological well-being. Negative affectivity is a personality trait that has been associated with discrimination. Yet, few studies to date have examined the longitudinal relationship between discrimination and personality.

Where you live matters: visualizing environmental effects on reading attainment.

Background: The way in which socioeconomic status (SES) moderates the etiology of reading attainment has been explored many times, with past work often finding that genetic influences are suppressed under conditions of socioeconomic deprivation and more fully realized under conditions of socioeconomic advantage: a gene-SES interaction. Additionally, past work has pointed toward the presence of gene-location interactions, with the relative influence of genes and environment varying across geographic regions of the same country/state.

Method: This study investigates the extent to which SES and geographical location interact to moderate the genetic and environmental components of reading attainment.

Examining mindset and grit in concurrent and future reading comprehension: A twin study.

Noncognitive factors have gained attention in recent years as potential intervention targets for academic achievement improvement in students. Two notable facets, intelligence mindset and grit, have been of particular interest. Both have been shown to consistently improve educational outcomes, although little work has focused on reading ability.

An investigation of the triarchic model of psychopathy and self-reported Cluster B personality disorder traits.

Cluster B personality traits often co-occur with psychopathic traits. However, few investigations have been conducted to understand the high co-occurrence of antisocial (ASPD), borderline (BPD), narcissistic (NPD), and histrionic (HPD) personality disorder traits and psychopathy. The triarchic model of psychopathy is a framework that focuses on dispositional constructs (meanness, boldness, and disinhibition) with neurobiological and developmental correlates that may be particularly useful in elucidating the overlap between Cluster B personality traits and psychopathy.

Twin Family Registries Worldwide: An Important Resource for Scientific Research.

Much progress has been made in twin research since our last special issue on twin registries (Hur, Y.-M., & Craig, J.

The Florida State Twin Registry.

The Florida State Twin Registry has existed for nearly two decades, and it grew primarily over 10 years as part of the Florida Learning Disability Research Center at Florida State University. The registry contains 2753 sets of twins and other multiples in Florida. The mean age of the sample currently is 17.

Early classroom reading gains moderate shared environmental influences on reading comprehension in adolescence.

Background: Reading is important for children's success in school and beyond, yet many adolescents fail to reach expected levels of proficiency. This highlights the need to better understand the factors that influence reading effectiveness over time, including genes and environment. Greater expression of genetic influence on first- and second-grade reading fluency has been observed in higher quality classroom reading environments.

The National Project on Achievement in Twins.

The National Project on Achievement in Twins (NatPAT) began in 2017 as part of the third funding cycle of the Florida Learning Disabilities Research Center, a program project grant funded by the Eunice Kennedy Shriver National Institute of Child Health and Development. NatPAT will have a nationally representative sample of elementary school-aged twins in the United States. The overall goal of the project is to uncover salient factors, including genetic and environmental influences, which contribute to the co-development of reading and math performance during the critical developmental period of elementary school.

Medical abortion with mifepristone and vaginal misoprostol between 64 and 70 days' gestation.

Objective: To evaluate outcomes with mifepristone 200 mg orally followed 24-48 h later by misoprostol 800 mcg vaginally for medical abortion at 64-70 days of gestation.

Study Design: We reviewed electronic databases and medical records for medical abortion cases at 64-70 days' gestation at British Pregnancy Advisory Service clinics in England and Wales from May 2015 through October 2016. Women selected in-office follow-up or self-evaluation of abortion outcome using a checklist along with low-sensitivity urine pregnancy testing.

The Developmental Propensity Model Extends to Oppositional Defiant Disorder: a Twin Study.

Previous research has supported the developmental propensity model, which proposes that three socioemotional dispositions (prosociality, negative emotionality, and daring) increase risk for the development of conduct problems through shared genetic and environmental influences. The current study extends this research by examining the model in relation to oppositional defiant disorder (ODD). Based on a confirmatory factor analysis, ODD was examined as three separate dimensions (irritable, headstrong, and hurtful) rather than a unitary construct.

Genetic and Environmental Influences on Achievement Outcomes Based on Family History of Learning Disabilities Status.

A risk to develop a learning disability has been shown to run in families. Having a positive family history of learning disability seems to account for mean differences in achievement outcomes (reading, math) in that children with a positive family history score significantly lower compared to their peers with no such family history. However, the role of family history status in explaining etiological (genetic and environmental) differences among these subgroups of children has yet to be established.

Outcomes of dilation and evacuation with and without feticide by intra-cardiac potassium chloride injection: a service evaluation.

Objective: To compare procedure duration, complications, and acceptability of dilation and evacuation (D&E) with and without feticide by intra-cardiac potassium chloride (KCL) injection.

Study Design: We evaluated outcomes with D&E at 18-24 weeks of gestation in the 6 months before and 6 months after removing feticide with KCL from the guidelines of a national British abortion provider. We extracted demographic and procedure-related data from medical records and electronic databases.

Examining the Etiology of Reading Disability as Conceptualized by the Hybrid Model.

A fairly recent definition of reading disability (RD) is that in the form of a hybrid model. The model views RD as a latent construct that is manifested through various observable unexpected impairments in reading related skills and through inadequate response to intervention. The current report evaluated this new conceptualization of RD from an etiological perspective.

The Effects of Genetic and Environmental Factors on Writing Development.

Researchers have identified sources of individual differences in writing across beginning and developing writers. The aim of the present study was to further clarify the sources of this variability by investigating the extent to which there are differences in genetic and environmental factors underlying the associations between lexical diversity, syntactic knowledge, and semantic cohesion knowledge in relation to writing. Differences were examined across two developmental phases of writing: beginning (i.

Home Environmental and Behavioral Risk Indices for Reading Achievement.

The goal of this study was to identify home environmental and temperament/behavior variables that best predict standardized reading comprehension scores among school-aged children. Data from 269 children aged 9-16 ( = 12.08; = 1.

Longitudinal Associations Among Reading-Related Skills and Reading Comprehension: A Twin Study.

This study investigated the etiology of longitudinal relations among kindergarten prereading skills, first-grade word level reading skills, and seventh-grade reading comprehension in 265 monozygotic and 459 dizygotic twin pairs (M  = 6.29 years in kindergarten) from the Florida Twin Project on Reading. Using a quadvariate Cholesky decomposition, results showed genetic, shared, and nonshared environmental overlap among prereading skills, word level reading skills, and reading comprehension.

Perceived Family Cohesion Moderates Environmental Influences on Prosocial Behavior in Nigerian Adolescent Twins.

Research shows that perceived family cohesion is positively related to prosocial behavior in adolescents. In this study, we investigated heritability of prosocial behavior (PB) and perceived family cohesion (FC) among Nigerian twins attending public schools in Lagos State, Nigeria (mean age = 14.7 years, SD = 1.

Oppositional defiant disorder dimensions: genetic influences and risk for later psychopathology.

Background: This study was undertaken to determine how well two oppositional defiant disorder (ODD) dimensions (irritable and headstrong/hurtful) assessed in childhood predict late adolescent psychopathology and the degree to which these outcomes can be attributed to genetic influences shared with ODD dimensions.

Methods: Psychopathology was assessed via diagnostic interviews of 1,225 twin pairs at ages 11 and 17.

Results: Consistent with hypotheses, the irritable dimension uniquely predicted overall internalizing problems, whereas the headstrong/hurtful dimension uniquely predicted substance use disorder symptoms.

Exploring the Co-Development of Reading Fluency and Reading Comprehension: A Twin Study.

This study explores the co-development of two related but separate reading skills, reading fluency and reading comprehension, across Grades 1-4. A bivariate biometric dual change score model was applied to longitudinal data collected from 1,784 twin pairs between the ages of 6 and 10 years. Grade 1 skills were influenced by highly overlapping genetic and environmental factors.