Publications by authors named "Jeanette M Watson"
Eur J Pharmacol
January 2009
Article Synopsis
- Xanomeline, an agonist for muscarinic acetylcholine receptors, reduces hyperactivity caused by amphetamine in wild-type (WT) mice.
- This reduction in activity is completely lost in mice that lack M(4) muscarinic receptors, and only partially reduced in those without M(1) receptors.
- The findings suggest that targeting M(4) receptors could be a potential strategy for treating psychosis in schizophrenia, while M(1) receptors might have a lesser role.
