Quantitative ultrasonic characterization yields information that is correlated to the tissue microstructure and increases the diagnostic potential of ultrasound. The measurement of acoustic properties of melanomas in vivo has not yet been reported after proton-beam irradiation. This prospective study was conducted on a cohort of 50 patients diagnosed with primary malignant melanoma to assess in vivo the ability of quantitative echography to detect changes in choroidal malignant melanomas after proton-beam irradiation and to follow the ultrasonographic changes during 24 months posttreatment.
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November 2003
We present a high precision ultrasonic velocimeter for a small volume sample (1 cm3) for a path length of 1 cm achieved. The method used is based on the time of flight measurement with an original signal processing technique: the barycenter method. With our system, we have measured the sound velocity with an accuracy of 10(-5).
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