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Publications by authors named "Jean-Sebastien Hoffmann"

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Synopsis of recent research by authors named "Jean-Sebastien Hoffmann"

  • - Jean-Sebastien Hoffmann's research primarily focuses on the mechanisms of DNA replication and repair, particularly in the context of cancer, highlighting how genetic factors and mutations influence tumorigenesis and treatment responses.
  • - His studies reveal critical insights into the roles of specific proteins, such as cytidine deaminase and DNA polymerase ε, in enhancing replication efficiency and genomic stability, as well as the impact of certain mutations on cancer aggressiveness and therapeutic outcomes.
  • - Hoffmann's findings underscore the importance of the molecular landscape of cancers, suggesting potential biomarkers and therapeutic strategies for improving cancer treatment, particularly for colorectal and pancreatic cancers.

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