Publications by authors named "Jean-Robert Klotoe"

Article Synopsis
  • Hepatic diseases pose a significant public health challenge, and traditional herbal treatments are commonly used in Benin for conditions like hepatitis, often without scientific evaluation.
  • The study assessed the hepatoprotective properties and toxicity of 10 herbal recipes by testing different plant varieties and their proportions in treated Wistar rats.
  • Findings indicated that the herbal recipes showed no acute toxicity and that their hepatoprotective effects increased with higher doses, with wild plant varieties performing better than cultivated ones, particularly when combined with certain other plants.
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Background: Child malnutrition is a major public health challenge, affecting millions of children worldwide, with alarming proportions of children under five in Benin. The complexity of managing this condition is increased by its potential association with opportunistic pathologies. An interesting approach arises from the use of medicinal plants, to address child malnutrition and its associated pathologies.

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Traditional medicine (TM) is a significant resource for primary healthcare management all over the world, and principally in Africa. Quality improvement activities that promote evidence-based practices and the integration of traditional medicine into primary healthcare systems can help improve the quality of patient care. In the Republic of Benin (West Africa), traditional medicine practitioners (TMPs) provide different treatments and ways of use, depending on the ailments and the medicinal plants used.

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Medicinal plants play a crucial role in the primary health care of the population in developing countries such as Benin. The national universities of Benin conduct research on the pharmacological, toxicological, and phytochemical properties of these plants, but the resulting knowledge often does not lead to the development of phytomedicines for the improvement of public health. This study aims to assess the current status of research on medicinal plants in Benin.

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Article Synopsis
  • - The study focuses on vulvovaginal candidiasis (VVC), a common infection linked to imbalances in vaginal health, aiming to assess its prevalence and related factors among women at Mènontin Hospital from March to August 2020.
  • - Data were gathered from 1,336 women's medical records, revealing a 56.25% prevalence of candidiasis among those with discharge, with no links found to age, marital status, or BMI, but connections were established with gestational age and characteristics of the discharge.
  • - Eight Candida species were identified as causing VVC, predominantly Candida dubliniensis and Candida albicans, highlighting the need for targeted control strategies based on the associated factors.
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Objective: Linn, Benth, and De Wild are three plants commonly used in the traditional treatment of urinary tract infections in Benin. This study sets out to assess the cytotoxic and teratogenic effects of extracts of these plants on larvae and hen embryos.

Methods And Results: The aqueous and ethanolic extracts were obtained by maceration of the powders in solvents.

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Previous work stated that , ., , , , , , and have a great potential for the fight against infectious diarrhea. However, data on their antibacterial activity on strains of bacteria responsible for infectious diarrhea are not available.

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The use of medicinal plants in traditional medicine is a common practice in developing countries. However, this unregulated or poorly rational use may present a dose-dependent risk of toxicity to humans. This study aimed to explore the phytochemical and toxicological characteristics of ten (10) plant species used in the traditional treatment of infectious diarrhea in Benin.

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Ethanol consumption is a risk factor of male infertility. The use of medicinal plants offers an alternative for the treatment of male infertility in developing countries. This study aimed to evaluate the Rourea coccinea effect on ethanol-induced male infertility in Wistar rats.

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Background: Candidiasis, an opportunistic cosmopolitan disease is nowadays like bacterial infections which is a real public health problem. In view of the emergence of Candida strains resistant to existing antifungal agents, alternative solutions should be considered. This is the purpose of this ethnobotanical survey, which aims to identify the medicinal plant species traditionally used to treat candidiasis in traditional markets of southern Benin.

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Objective: Hypercholesterolemia is the greatest risk factor for cardiovascular diseases. The present study is conducted to evaluate the lipid lowering activity of leaves and fruits of Solanum macrocarpon, a vegetable, on Wistar rats experimentally rendered hypercholesterolemic by Triton X-100.

Materials And Methods: The leaves and fruits were administered (p.

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This work assesses the impact of the use of chicken manure and irrigation water on the toxicological quality of Solanum macrocarpon, a highly appreciated vegetable. A control site in Glo-Djigbé, gardeners' sites at Houéyiho, Fidjrossè, and Agongbomey were included in the study. Lead has been sought in the environment of S.

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