One half of patients reports persistent pain three months after orthopaedic surgery.

Objective: To determine persistent post-surgical pain prevalence after orthopaedic surgery with its impact on patient quality of life and to assess factors related to it.

Study Design: Cross-sectional cohort study.

Patients: A questionnaire was mailed to 2100 patients undergoing orthopaedic surgery in our teaching hospital.

Spinal anesthesia failure after local anesthetic injection into cerebrospinal fluid: a multicenter prospective analysis of its incidence and related risk factors in 1214 patients.

Background And Objectives: Different mechanisms have been proposed to explain spinal anesthesia failure even after LA injection into the subarachnoid space. The aim of this prospective multicenter study was to assess the incidence of spinal anesthesia failure, excluding technical problems, and then to suggest independent factors leading to failure.

Methods: Consecutive spinal anesthetic procedures performed in 21 centers were included.