A collaborative study involving 25 laboratories assessed the effectiveness of a nontarget data acquisition (nDATA) workflow for screening pesticides in high moisture produce using advanced liquid chromatography-high-resolution mass spectrometry techniques.*
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The study employed a quick and efficient sample extraction method (QuEChERS) and focused on identifying 51 pesticides, ensuring accuracy through strict criteria for retention time and mass errors.*
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Results showed high consistency in pesticide elution profiles among laboratories and low false positive/negative rates (1.1%, 0.7%, and 0.1% respectively), indicating the potential for reliable routine analysis after further evaluations.*
This work focused on developing a method to determine the volatile compounds that contribute to individual masses observed by PTR-MS in the headspace of a food product (e.g., cheese crackers).