Publications by authors named "Jean-Paul Niguet"
The recreational use of nitrous oxide (N2O) is an emerging public health issue. Chronic N2O abuse may result in various clinical symptoms, encompassing neurological, psychiatric and cardiovascular outcomes. Despite the difficulties for the laboratory investigation of N2O intoxication, there is currently no guidelines in France to help both clinicians and biologists use appropriate biomarkers for the diagnosis and monitoring of patients with clinical symptoms potentially related to N2O intoxication.
View Article and Find Full Text PDFThe recreational use of nitrous oxide (NO), also called laughing gas, has increased significantly in recent years. In 2022, the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA) recognized it as one of the most prevalent psychoactive substances used in Europe. Chronic nitrous oxide (NO) exposure can lead to various clinical manifestations.
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- - The study aimed to analyze EEG patterns in critically ill COVID-19 patients suspected of having encephalopathy and how these patterns relate to their clinical outcomes.
- - Of the 33 patients analyzed, abnormal EEG findings included slowed activity in 85% of cases, with significant associations noted between unreactive patterns and poor clinical outcomes at 14 days.
- - The research suggests that the specific EEG abnormalities observed may indicate encephalopathy and are useful in predicting short-term recovery in COVID-19 patients.