Publications by authors named "Jean-Michel Etienne"
In an ineffective transfusion context, solid-phase immunoassays using the Luminex platform for the detection and characterization of HLA antibodies are currently used to select HLA-compatible platelet products. A new HLA antibody identification method, the HISTO SPOT® HLA AB test (BAG Health care GmbH, Lich, Germany), based on the detection of antibodies directed against a recombinant single antigen (SA) by colored spots detected by HISTO MATCH HLA AB module software, runs fully automated on the MR.SPOT®.
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- The INTERCEPT Blood System has been utilized in France for three years to reduce pathogen load in platelet concentrates, specifically for patients with acute myeloid leukemia (AML).
- A study on 176 patients compared the effectiveness of pathogen-reduced platelets (PR_PLT) versus untreated platelet products (U_PLT) in preventing bleeding and assessed transfusion efficiency through 24-hour corrected count increment (24h_CCI) and the time to the next transfusion.
- Results showed that higher doses of PR_PLT (>0.65×10/10 kg) led to similar 24h_CCI compared to U_PLT, facilitating transfusions every 48 hours, while lower doses were less effective in managing bleeding, highlighting
The paper investigates the effects of nursing overtime on nosocomial infections and medical accidents in a neonatal intensive care unit (NICU). The literature lacks clear evidence on this issue and we conjecture that this may be due to empirical and methodological factors. We model the occurrences of both events using a sample of 3979 neonates who represents over 84,846 observations (infant/days).
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