Integrin alpha 6 homozygous splice-site mutation causes a new form of junctional epidermolysis bullosa in Charolais cattle.

Background: Inherited epidermolysis bullosa (EB) is a group of painful and life-threatening genetic disorders that are characterized by mechanically induced blistering of the skin and mucous membranes. Congenital skin fragility resembling EB was recently reported in three Charolais calves born in two distinct herds from unaffected parents. Phenotypic and genetic analyses were carried out to describe this condition and its molecular etiology.

Cutaneous and systemic granulomatous disease associated with hairy vetch toxicosis in a French Holstein dairy herd.

This report describes an outbreak of hairy vetch toxicosis afflicting a herd of cattle with a fatal cutaneous and systemic granulomatous disease. It highlights how this condition remains poorly recognized by cattle production professionals in Europe and the need for communication about vetch-associated diseases.

Multiple congenital epitrichial sweat gland hamartomas in a piglet.

A case of multiple congenital epitrichial sweat gland hamartomas in a 2-day-old piglet is presented. The skin lesions were raised, ovoid to linear in configuration, alopecic, red-purple to pink, and cauliflower-like to cerebriform in appearance. Histological examination of skin specimens confirmed a diagnosis of epitrichial sweat gland hamartoma.

Detection by PCR-enzyme-linked immunosorbent assay of Clostridium botulinum in fish and environmental samples from a coastal area in northern France.

The prevalence of Clostridium botulinum types A, B, E, and F was determined in 214 fresh fish and environmental samples collected in Northern France. A newly developed PCR-enzyme-linked immunosorbent assay (ELISA) used in this survey detected more than 80% of samples inoculated with fewer than 10 C. botulinum spores per 25 g and 100% of samples inoculated with more than 30 C.

Myxomatosis of the Depilated Angora rabbit. A Preliminary Study.

Abstract- A nodular eruption occurring on the skin of depilated Angora rabbits was studied at 47 rabbit farms in 1988. Virus isolation, electron microscopy, transmission experiments and comparison with experimental infection using recognised strains of myxoma virus confirmed that the disease was myxomatosis. The disease occurred particularly in July and August in rabbits vaccinated in March or April with the heterologous vaccine.

Bovine Nodular Thelitis: a Clinicopathological Study of 20 Cases.

Abstract- Bovine nodular thelitis in dairy cows is a chronic and enzootic infection. Four stages were distinguished: early stage, evolutive stage, ulcerative stage and final stage. Lesions were located mainly in the lower part of the udder or on the teat and recognized as solid papules and nodules.