Publications by authors named "Jean-Marc Rosenthal"

Article Synopsis
  • * The exposure rates for gentamicin and amikacin were 31.7% and 9.1%, respectively, with a significant majority of treatments starting within the first week of life, and changes in average daily doses noted over the years.
  • * The study found low rates of overdose and underdose for both antibiotics, with factors such as year of admission and prematurity influencing gentamicin overdose rates, suggesting the effectiveness of a
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Objectives: The primary objective of this study is to determine the current level of patient medication exposure in Level 3 Neonatal Wards (L3NW). The secondary objective is to evaluate in the first month of life the rate of medication prescription not cited in the Summary of Product Characteristics (SmPC). A database containing all the medication prescriptions is collected as part of a prescription benchmarking program in the L3NW.

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Article Synopsis
  • A significant Zika virus outbreak occurred in French Guiana and the West Indies from January to October 2016, with 1650 pregnant women affected.
  • ZIKV infection during pregnancy is linked to serious birth defects like microcephaly, but in this case, two children born from mothers with symptomatic infections showed no immediate abnormalities at birth.
  • Despite initial healthy appearances, both children later exhibited severe brain abnormalities related to in utero ZIKV exposure detected through MRI, suggesting potential implications of the mother's immune response or metabolic changes during infection.
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