Study of the influence of coating methods on lipid spheres manufactured on rotor fluidized bed process.

Different previous works have shown that various kinds of spheres can be manufactured by rotor granulation in a 'single-pot process' using a lipid base: hydrogenated castor oil. This single-pot technology is based on wet granulation where all components are placed in the powder form in the rotor bowl; then, they are continuously suspended in a fluidized air, with a tangentially sprayed liquid solution. This process allows the granulation and manufacturing of sphere during the same time.

Active spermatogenesis induced by a reiterated administration of Globularia alypum L. aqueous leaf extract.

Background: Globularia alypum L. (Globulariaceae) is a shrub growing in the Mediterranean basin and known to be used as a popular medicine for its several pharmacological properties against rheumatism, gout, typhoid, intermittent fever, and diabetes.

Materials And Methods: The acute and chronic toxicities of a G.

The relaxant effect induced by Allium sativum L. bulb aqueous extract on rat isolated trachea.

Background: Garlic plays an important role in complementary and alternative medicine. Most people believe in and use herbal products even when they have not been as thoroughly researched as garlic. Garlic is also known for its beneficial effects on the cardiovascular system.

Single process for manufacturing spheres with a lipid base (HCO).

Pellets and spheres are manufactured in the pharmaceutical industry by various processes which are not always easily automated. In this paper, a 'single pot process' is described using rotary fluid bed granulation with lipid fillers. This technology is based on wet granulation of powder components, continuously suspended in a fluidized air with a tangentially sprayed liquid solution.

An overview about biopharmaceutics in Europe.

In Europe, the concept of biopharmaceutics was first introduced at the end of the 70s by various highly informed young Europeans who took into full account the publications and studies carried out by the first generation of explorers in this area in the United States such as John Wagner, Gerhard Levy, and W.A. Ritschel, amongst others.