[Telemedicine in pediatric dermatology:focus on current practices].

Pediatric teledermatology (PTD) allows offering long distance health care advice in pediatric dermatology trough telecommunication technologies. Due to the lack of pediatric dermatologists, the frequency of dermatological questions in general pediatrics, the visual nature of the specialty, and the rare occurrence of vital emergencies in dermatology, PTD appears to be a good option for giving long distance advice in a certain number of skin conditions. In this article, we will discuss benefits and limitations of PTD.

[Reflectance confocal microscopy : what future for dermatology ?].

Reflectance confocal microscopy is a non invasive imaging technique which provides in vivo and real time images of different skin tissues with a resolution close to histology, however with a depth limited to superficial dermis.The first lesions that were morphologically analyzed are melanocytic lesions. Reflectance confocal microscopy has been used for about ten years in dermatology.

A pilot study using reflectance confocal microscopy (RCM) in the assessment of a novel formulation for the treatment of melasma.

Introduction: Melasma is a common pigmentary disorder caused by abnormal melanin deposits within the skin. Hydroquinone (HQ) is presently the most popular depigmenting agent, however the treatment of melasma remains unsatisfactory, resulting in a need to evaluate new depigmenting agents.

Objective: The objective of this study was to assess, using standard methods and a novel technique, in vivo Reflectance Confocal Microscopy (RCM), the efficacy and safety of a new non-HQ bleaching agent Dermamelan® (Mesoestetic, Barcelona, Spain) in the treatment of melasma.

Efficacy of a novel intense pulsed light system for the treatment of port wine stains.

Background And Objectives: Port wine stains (PWS) are capillary malformations typically treated with lasers or with intense pulsed light (IPL). This paper summarizes our safety and efficacy findings for a new IPL designed to target the dermal vessels of PWS.

Methods: The PWS received three to four treatments with a novel IPL containing a vascular-specific handpiece (LuxG, dual wavelength band of 500-670 nm and 870-1400 nm; Palomar Medical Technologies, Inc.

In vitro evaluation of the effect of electrotreatment on skin permeability.

Background: Stratum corneum composition and structure limit cutaneous bioavailability of pharmaceutical and cosmetical agents. Electrically assisted transport can increase the rate and extent of delivery; moreover, it also enables the administration of polar and charged molecules into the skin.

Aims: The objective of this study was to investigate the effect of electrotreatment on skin permeability by measuring the cumulative delivery of caffeine and sodium ascorbyl phosphate.

Results of fractional ablative facial skin resurfacing with the erbium:yttrium-aluminium-garnet laser 1 week and 2 months after one single treatment in 30 patients.

The erbium:yttrium-aluminium-garnet (Er:YAG) laser has recently been used in the fractional resurfacing of photo-aged skin. Our study evaluated the results after one single session of fractional resurfacing with Er:YAG. Thirty women participated in the study, with an average age of 46 years, skin types from II to IV, and wrinkle grades I to III.

Combined effects of silymarin and methylsulfonylmethane in the management of rosacea: clinical and instrumental evaluation.

Objective: This study aims to evaluate a topical treatment based on silymarin/methylsulfonilmethane (S-MSM) to improve erythematous-telangiectactic rosacea.

Methods: Forty-six patients affected by stage I-III rosacea entered this double-blind, placebo-controlled study. Subjects were treated for 1 month.

A double-blind controlled study of a nonhydroquinone bleaching cream in the treatment of melasma.

Background: Melasma is an acquired hypermelanosis predominantly affecting the face of women. It is often recalcitrant to treatment with hypopigmenting agents.

Objective: To assess the efficacy of a nonhydroquinone cream (Amelan M) vs.

Efficacy of nonablative laser treatment for rhytids: a controlled study with objective evaluation via clinical, profilometric, and computer assessments.

Background: A 980-nm diode laser was evaluated in rhytids treatment to ascertain its short- and long-term efficacy, as well as its potential value as an adjunct to aesthetic surgery.

Subjects And Methods: Twenty subjects, 10 in each of 2 geographically distant sites, were treated with a 980-nm diode laser (macropulse of 1.9 seconds, two 200-ms micropulses, 25 J/cm(2) each).

Treatment of vascular abnormalities with a long-pulse diode at 980 nm.

Background: Lasers have been used to treat a variety of vascular abnormalities for over 20 years. For minor vascular targets, a small and friendly diode laser with cooling handpiece appears to be a challenger to other systems.

Objective: The purpose of this study was to compile treatment data and to examine the effectiveness of a longer pulse duration diode laser in the treatment of vascular pathologies such as facial telangiectasia, venous lakes, spider nevi, blue telangiectasia, leg veins and dermatological treatments.

Botulinum toxin A: a 9-month clinical and 3D in vivo profilometric crow's feet wrinkle formation study.

Objective: The objective of this study was to determine the duration of the effects of a defined dose of BTX-A on crow's feet formation wrinkles.

Materials And Methods: Twenty-five patients each received one injection of 12 units of BTX-A in the orbicularis oculi muscle on both sides of the face. The results were evaluated at 3, 6 and 9 months.

Non-ablative skin remodeling: an 8-month clinical and 3D in vivo profilometric study with an 810 nm diode laser.

Background: Non-ablative remodeling has recently been proposed as a new anti-aging treatment with no downtime.

Objective: This study aimed to evaluate objectively, with a three-dimensional (3D) in vivo profilometric study, the efficacy and safety of non-ablative skin remodeling with an 810 nm diode laser on periorbital wrinkles with an 8-month follow-up.

Methods: Ten female patients (mean age: 55 years) were treated three times at 1-month intervals and then evaluated 5 months after the last treatment.

Comparison and sequential study of long pulsed Nd:YAG 1,064 nm laser and sclerotherapy in leg telangiectasias treatment.

Background And Objectives: Millisecond pulsed 1,064 nm Nd:YAG lasers have been developed for the treatment of leg telangiectasias. To date there have been very few side by side comparison studies of laser versus the gold standard sclerotherapy in treating small leg veins. This study aims to compare a long pulsed Nd:YAG laser with contact cooling to sclerotherapy for treating small diameter leg telangiectasias by evaluating objective and subjective clinical effects.

New operative technique for treatment of xanthelasma palpebrarum: laser-inverted resurfacing: preliminary report.

Xanthelasma palpebrarum lesions are benign but present cosmetic problems to the patient. Their surgical removal has also presented problems to the surgeon. A new laser operative technique for xanthelasma palpebrarum is introduced to avoid the risk for scarring and pigmentary changes after vaporization of eyelid tissue to remove benign lesions, for example, xanthelasma.