Risk Factors for a Severe Bleb Leak Following Trabeculectomy: A Retrospective Case-Control Study.

Purpose: To describe the population at risk of having a severe bleb leak needing a surgical repair in the operating room and to study risk factors associated with severe bleb leak.

Patients And Methods: In this case-control study, 17 cases were enrolled and paired with 51 controls. We studied all patients having a surgical revision in our center for a severe bleb leak between January 1 and December 31, 2008.

Transconjunctival suturing of the scleral flap for overfiltration with hypotony maculopathy after trabeculectomy.

Objective: To assess the efficacy of transconjunctival suturing of the scleral flap in improving hypotony maculopathy resulting from overfiltration after trabeculectomy.

Design: Retrospective review.

Participants: 35 eyes of 33 patients.

Founder TIGR/myocilin mutations for glaucoma in the Québec population.

Primary open-angle glaucoma (POAG) is a complex disorder characterized by a progressive and treatable degeneration of the optic nerve. TIGR/myocilin (MYOC) gene mutations are found in approximately 4% of all POAG patients. Populations with frequent founder effects, such as the French-Canadians, offer unique advantages to implement genetic testing for the disorder.