Publications by authors named "Jean-Joseph Bendjilali-Sabiani"

Article Synopsis
  • A new liquid chromatography-tandem mass spectrometry method has been created to measure 11 antifungal drugs and their metabolites in human plasma, essential for monitoring treatment in immunocompromised patients with fungal infections.
  • * This method not only optimizes settings and preparation techniques for accurate detection but also follows strict FDA and EMA guidelines to ensure reliability and performance.
  • * With a quick processing time of 5 minutes per sample and minimal plasma requirement, this method supports better antifungal therapy management in critical care settings.
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From 2019, in the United States and Europe, the synthetic opioid market has diversified with the appearance of the 2-benzylbenzimidazole family, commonly named "nitazenes". In vitro studies show that these synthetic opioids have much higher affinities on μ-opioid receptors: 100 times more than morphine, and slightly higher than fentanyl for isotonitazene, increasing the risk of overdose. In south of France, isotonitazene (IZN) was identified for the first time in March 2023.

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