Publications by authors named "Jean-Francois Laurent"

Objectives: Sports coaches are influential in whether athletes dope, but receive very little antidoping education, particularly within entry-level coaching qualifications. We tested the feasibility of an antidoping intervention, delivered via a mobile application, which was designed to increase coaches' knowledge of doping and to reduce favourable doping attitudes.

Methods: A two-arm randomised controlled trial, with grassroots coaches who coach young amateur athletes aged between 14 and 18 years of age, was conducted.

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Taking performance-enhancing drugs (PEDs) can cause serious and irreversible health consequences, which can ultimately lead to premature death. Some young people may take PEDs without fully understanding the ramifications of their actions or based on the advice from others. The purpose of this systematic review was to identify the main factors that predicted doping among young people.

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High amount of relevant information is contained in reports stored in the electronic patient records and associated metadata. R-oogle is a project aiming at developing information retrieval engines adapted to these reports and designed for clinicians. The system consists in a data warehouse (full-text reports and structured data) imported from two different hospital information systems.

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Unlabelled: Isolated skin recurrence after mastectomy (ISRAM) for breast cancer is a rare event for which treatment is difficult and subject to debate.

Patients And Methods: The records of 75 patients presenting with ISRAM were reviewed retrospectively. The factors liable to affect recurrence prognosis were analyzed, and included both factors related to the primary tumor and its treatment and those related to the recurrence itself.

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Introduction: Epidermoid and dermoid cysts are among the most benign intra cranial tumors. Their malignant transformation into squamous cell carcinoma is rare. The authors reviewed the literature.

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Purpose: Previous studies have shown that the use of Lipiodol UltraFluid (LUF) emulsified with water leads to an increase in the tumoral uptake of iodine I 131-labeled LUF and reduced pulmonary uptake. Although emulsions containing LUF are currently used for chemoembolization of hepatocellular carcinomas (HCCs), this approach is impossible with intraarterial radiation therapy (RT) because of the problems of radiation protection linked to instability of the emulsions. The aims of this study were to develop stabilized emulsions of radiolabeled LUF of different particle sizes and viscosities and to study its biodistribution in rats with HCC.

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In most hospital medical units, multidisciplinary committees meet weekly to discuss their patients' cases. The medical experts base their decisions on three sources of information. First, they check if their patient complies with existing guidelines.

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When a new patient does not comply with the guidelines, experts base their therapeutic decisions on similar patients' cases they have treated in the past. The case-based reasoning decision-support system we propose will automatically compare the patient's case to the structured guideline, then to other cases, and retrieve similar cases. The general structure of the system is presented here, the domain of application being oncology.

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The process of transmitting patient medical information between different healthcare parties involves harmonizing multiple elements: addresses, certificates, patient IDs, communication protocol, message format, and documents/EPR to be exchanged. Beyond the work done at the "information structure level" within CEN TC251, ISO TC215, HL7 and DICOM, it is necessary to focus on the "basic medical communication level." An original approach, based on the "Patient Envelope", has been developed and successfully implemented for Oncology.

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Through the implementation of the French reform of resources allocation, according to the French DRG system (PMSI), all the medical records of French hospitals are currently indexed according to the same rules and classifications. As a by-product, these discharge summaries are merged into huge administrative databases covering both public and private settings. Statistical analysis of these data have begun, and seems to be worthwhile in oncology, e.

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