Effect of Simulated Tooth Brushing on Surface Roughness, Gloss, and Color Stability of Milled and Printed Permanent Restorative Materials.

Objectives: This in vitro study evaluated the effects of simulated toothbrushing on surface roughness, gloss, and color stability of milled and printed resin-based and lithium disilicate materials for permanent dental restorations.

Materials And Methods: Five materials were tested, including CAD/CAM prepolymerized resin blocks, a ceramic material, a resin composite and a newly FDA-cleared 3D-printed resin for permanent crowns. Specimens underwent a controlled brushing protocol simulating 5 years of brushing (50,000 cycles).

Inference of the Mass Composition of Cosmic Rays with Energies from 10^{18.5} to 10^{20} eV Using the Pierre Auger Observatory and Deep Learning.

We present measurements of the atmospheric depth of the shower maximum X_{max}, inferred for the first time on an event-by-event level using the surface detector of the Pierre Auger Observatory. Using deep learning, we were able to extend measurements of the X_{max} distributions up to energies of 100 EeV (10^{20}  eV), not yet revealed by current measurements, providing new insights into the mass composition of cosmic rays at extreme energies. Gaining a 10-fold increase in statistics compared to the fluorescence detector data, we find evidence that the rate of change of the average X_{max} with the logarithm of energy features three breaks at 6.

Perioperative infarction during coronary bypass surgery: an attempt to refine the diagnostic criteria using data from a retrospective case-control study.

Objective: The definition of coronary artery bypass graft (CABG)-associated myocardial infarction (MI) is controversial because the postoperative increases in cardiac enzyme activities are multifactorial in origin.

Methods: We performed a retrospective case-control study of patients who experienced perioperative MI (cardiac enzyme release, electrocardiographic changes, dysfunction on echocardiography) and those without ischemia to identify risk factors and enzyme activity thresholds.

Results: The estimated incidence of CABG-associated MI was 2.

Horticultural additives influence peat biogeochemistry and increase short-term CO production from peat.

Aims: Peat is used as a major ingredient of growing media in horticulture. Peat extracted from bogs can be acidic and low in nutrient availability and is therefore mixed with liming agents, nutrients, surfactants, perlite and so on. This study aims to estimate the rates at which raw peat and the modified peat ('growing media') decompose to release carbon dioxide (CO), to estimate the release of carbon (C) from liming agents and to estimate how peat biogeochemistry is changed.

Is Strength the Main Risk Factor of Overuse Shoulder Injuries? A Cohort Study of 296 Amateur Overhead Athletes.

Background: Shoulder pain is one of the most common musculoskeletal complaints in overhead athletes. This study investigated the prevalence of the main risk factors and sex differences related to the development of shoulder pain in a cohort of amateur overhead athletes.

Hypothesis: The external rotation/internal rotation (ER/IR) isometric strength ratio <0.

Should I prescribe exercise to a patient with an immobilized shoulder? An electromyographic study in patients with unilateral shoulder pain and healthy volunteers.

Background: There is limited evidence about exercise performance during postoperative immobilization. This study aimed to quantify the muscle activity in the immobilized shoulder girdle in an abduction and neutral rotation position during a battery of contralateral activities and ipsilateral exercises of the upper limb in healthy volunteers and patients with unilateral shoulder pain (USP).

Methods: Thirty participants were included and grouped as without ( = 17) or with USP ( = 13).

Kidney cancer following occupational exposure to trichloroethylene: Clinical case series and review of the literature.

Introduction: This case study describes the clinical, medical and administrative management of kidney cancer secondary to occupational exposure to trichloroethylene, a chlorinated solvent classified as a known carcinogen by the International Agency for Research on Cancer.

Method: Data were collected from the computerized records of all patients treated by the occupational medicine department of Montpellier University Hospital for kidney cancer following occupational exposure to trichloroethylene.

Results: The study included five patients aged between 36 and 64years.

Physicochemical properties of flowable composites using isobornyl methacrylate as diluent monomer.

Objective: this study sought to evaluate the effect of isobornyl methacrylate (IBOMA) as a diluent monomer on the physicochemical properties of experimental flowable resin composites.

Methodology: the organic resin matrix of a modal flowable resin composite was formulated with 50 wt.% of bisphenol-A-glycidyl methacrylate (Bis-GMA) and 50 wt.

Spin Dynamics across Metallic Layers on the Few-Femtosecond Timescale.

We measure the light-driven response of a magnetic multilayer structure made of thin alternating layers of cobalt and platinum at the few-femtosecond timescale. Using attosecond magnetic circular dichroism, we observe how light rearranges the magnetic moment during and after excitation. The results reveal a sub-5 fs spike of magnetization in the platinum layer, which follows the shape of the driving pulse.

Current and future workforce of general internal medicine in Switzerland: a cross-sectional study.

Aim Of This Study: General internal medicine is a crucial element in healthcare systems. Understanding how many people are and will be working in this field is important to maintain and improve quality for patients in healthcare systems. This can provide a basis for political decisions.

It's not who you know, but who you are: Explaining income gaps of stigmatized-caste business owners in India.

Scholars across disciplines and around the world have diverted research attention to rising income inequalities across groups and strategies to reduce them. The literature has broadly identified human capital and social capital as two potential tools to facilitate economic mobility and to reduce inequalities. However, it is not known whether these tools work equally well for stigmatized groups, particularly in societies with systemic inequalities.

Wind as a Driver of Peat CO Dynamics in a Northern Bog.

Unlabelled: Excess CO accumulated in soils is typically transported to the atmosphere through molecular diffusion along a concentration gradient. Because of the slow and constant nature of this process, a steady state between peat CO production and emissions is often established. However, in peatland ecosystems, high peat porosity could foster additional non-diffusive transport processes, whose dynamics may become important to peat CO storage, transport and emission.

Horizontally transferred mitochondrial DNA tracts become circular by microhomology-mediated repair pathways.

The holoparasitic plant Lophophytum mirabile exhibits remarkable levels of mitochondrial horizontal gene transfer (HGT). Gathering comparative data from other individuals and host plants can provide insights into the HGT process. We sequenced the mitochondrial genome (mtDNA) from individuals of two species of Lophophytum and from mimosoid hosts.

Effect of butylated hydroxytoluene (BHT) concentrations on polymerization shrinkage stress and other physicochemical properties of experimental resin composites.

The present study examined different concentrations of the butylated hydroxytoluene (BHT) inhibitor on the kinetics of conversion, polymerization shrinkage stress, and other correlated physicochemical properties of experimental resin composites (ERC). A model composite was formulated with 75 wt% filler containing 0.5 wt% camphorquinone and 1 wt% amine with BHT concentrations of 0.

Pharmacological PINK1 activation ameliorates Pathology in Parkinson's Disease models.

PINK1 loss-of-function mutations and exposure to mitochondrial toxins are causative for Parkinson's disease (PD) and Parkinsonism, respectively. We demonstrate that pathological α-synuclein deposition, the hallmark pathology of idiopathic PD, induces mitochondrial dysfunction, and impairs mitophagy as evidenced by the accumulation of the PINK1 substrate pS65-Ubiquitin (pUb). We discovered MTK458, a brain penetrant small molecule that binds to PINK1 and stabilizes its active complex, resulting in increased rates of mitophagy.

Performance evaluation of the Access HBsAg and Access HBsAg confirmatory assays on the DxI 9000 Access Immunoassay Analyzer.

Introduction: This study evaluated the clinical and analytical performances of the Access HBsAg and the Access HBsAg Confirmatory assays on the DxI 9000 Access Immunoassay Analyzer (Beckman Coulter, Inc.).

Materials And Methods: Diagnostic specificity and sensitivity of the Access HBsAg and Access HBsAg Confirmatory assays were evaluated by comparing the Access assays to the final HBsAg sample status determined using the Architect, PRISM, or Elecsys HBsAg assays, along with Architect or PRISM HBsAg Confirmatory assays.

Long-term results of conversion of Roux-en-Y to biliopancreatic diversion with duodenal switch.

Background: Despite the fact Roux-en-Y gastric bypass (RYGB) is one of the most efficient bariatric procedures, postoperative weight regain still can be seen.

Objectives: To retrospectively assess the early outcomes and up to 10-year weight results of the conversion of RYGB to biliopancreatic diversion with duodenal switch (BPD-DS).

Setting: French private hospital, 2-surgeon practice in a bariatric surgery center with an experience of >20 RYGB procedures.

Demonstrating Agreement between Radio and Fluorescence Measurements of the Depth of Maximum of Extensive Air Showers at the Pierre Auger Observatory.

We show, for the first time, radio measurements of the depth of shower maximum (X_{max}) of air showers induced by cosmic rays that are compared to measurements of the established fluorescence method at the same location. Using measurements at the Pierre Auger Observatory we show full compatibility between our radio and the previously published fluorescence dataset, and between a subset of air showers observed simultaneously with both radio and fluorescence techniques, a measurement setup unique to the Pierre Auger Observatory. Furthermore, we show radio X_{max} resolution as a function of energy and demonstrate the ability to make competitive high-resolution X_{max} measurements with even a sparse radio array.

Timing matters: Early versus late rib fixation in patients with multiple rib fractures and pulmonary contusion.

Background: Recent literature has shown that surgical stabilization of rib fractures benefits patients with rib fractures accompanied by pulmonary contusion; however, the impact of timing on surgical stabilization of rib fractures in this patient population remains unexplored. We aimed to compare early versus late surgical stabilization of rib fractures in patients with traumatic rib fractures and concurrent pulmonary contusion.

Methods: We selected all adult patients with isolated blunt chest trauma, multiple rib fractures, and pulmonary contusion undergoing early (<72 hours) versus late surgical stabilization of rib fractures (≥72 hours) using the American College of Surgeons Trauma Quality Improvement Program 2016 to 2020.

Current practices of physiotherapists in Switzerland regarding fall risk-assessment for community-dwelling older adults: A national cross-sectional survey.

Background: Falls can strongly impact older people's quality of life, health, and lifestyle. Multifactorial assessment can determine an individual's risk of falling as the first step for fall prevention intervention. Physiotherapists have an essential role to play in assessing fall risk by older adults living in the community.

Cross-alteration of murine skin and tick microbiome concomitant with pathogen transmission after Ixodes ricinus bite.

Background: Ticks are major vectors of diseases affecting humans such as Lyme disease or domestic animals such as anaplasmosis. Cross-alteration of the vertebrate host skin microbiome and the tick microbiome may be essential during the process of tick feeding and for the mechanism of pathogen transmission. However, it has been poorly investigated.

Effect of elastomeric urethane monomer on physicochemical properties and shrinkage stress of resin composites.

This study aimed to evaluate the effect of an elastomeric urethane monomer (Exothane-24) in different concentrations on physicochemical properties, gap formation, and polymerization shrinkage stress of experimental resin composites. All experimental composites were prepared with 50 wt.% of Bis-GMA and 50 wt.

Evaluating the impact of timing to rib fixation in patients with traumatic brain injury: A nationwide analysis.

Background: Early surgical stabilization of rib fractures (SSRF) is associated with improved inpatient outcomes in patients with multiple rib fractures. However, there is still a paucity of data examining the optimal timing of SSRF in patients with concomitant traumatic brain injury (TBI). This study aimed to assess whether earlier SSRF was associated with improved outcomes in patients with multiple rib fractures and TBI.

Timing of regional analgesia in elderly patients with blunt chest-wall injury.

Background: Rib fractures represent a typical injury pattern in older people and are associated with respiratory morbidity and mortality. Regional analgesia modalities are adjuncts for pain management, but the optimal timing for their initiation remains understudied. We hypothesized that early regional analgesia would have similar outcomes to late regional analgesia.