Publications by authors named "Jean-Claude Legrand"
HIV positive asylum seekers receiving the order to leave the Belgian territory.
J Int AIDS Soc
January 2016
Introduction: In a human rights based approach, the Parliamentary Assembly of the Council of Europe has recently released a resolution about migrants and refugees and the fight against HIV (1). It states that "an HIV positive migrant should never be expelled when it is clear that he will not receive adequate health care and assistance in the country to which he is being sent back. To do otherwise would amount to a death sentence for that person.
View Article and Find Full Text PDFArticle Synopsis
- Tenofovir (TDF) is an antiretroviral drug used for HIV treatment, but it may cause kidney issues like proteinuria and decline in kidney function, prompting guidelines for monitoring patients.
- The study collects blood and urine samples from 300 patients over two years to assess kidney function and the effectiveness of EACS screening criteria for diagnosing proximal renal tubular dysfunction (PRTD).
- Results reveal the number of PRTD cases among TDF users and how many of them met EACS screening criteria, suggesting a need for better screening practices in clinical settings.
Maintenance with a triple nucleoside reverse transcriptase Inhibitor (NRTI) regimen after successful induction with a dual NRTI/protease inhibitor (PI) combination may be advantageous, because of low pill burden, favorable lipids, and less drug interactions. This strategy to become free of PI-related problems without losing viral efficacy has not been formally tested. We performed a randomized, open-label, multicenter, 96-week comparative study in antiretroviral therapy (ART)-naïve patients with CD4