Publications by authors named "Jean-Christophe Ruzic"
Article Synopsis
- The study utilized the NETSARC database to analyze management and outcomes of adolescents and young adults (AYAs) with sarcoma in France from 2010 to 2017, focusing on surgical cases.
- Findings showed significant discrepancies in adherence to treatment guidelines between patients treated at reference sarcoma centers (RSC) and non-reference centers (non-RSC), with RSC having better rates of crucial pre-treatment procedures.
- Despite similar overall survival rates (OS) for AYAs in both settings, those treated in RSC had notably better locoregional recurrence-free survival (LRFS) and progression-free survival (PFS), underscoring the benefits of multidisciplinary care in specialized centers.
Background: This French nationwide NETSARC exhaustive prospective cohort aims to explore the impact of systematic re-excision (RE) as adjuvant care on overall survival (OS), local recurrence free survival (LRFS), and local and distant control (RFS) in patients with soft tissue sarcoma (STS) with positive microscopic margins (R1) after initial resection performed outside of a reference center.
Methods: Eligible patients had experienced STS surgery outside a reference center from 2010 to 2017, and had R1 margins after initial surgery. Characteristics and treatment comparisons used chi-square for categorical variables and Kruskall-Wallis test for continuous data.
The national reference network NETSARC+ provides remote access to specialized diagnosis and the Multidisciplinary Tumour Board (MTB) to improve the management and survival of sarcoma patients in France. The IGéAS research program aims to assess the potential of this innovative organization to address geographical inequalities in cancer management. Using the IGéAS cohort built from the nationwide NETSARC+ database, the individual, clinical, and geographical determinants of the 3-year overall survival of sarcoma patients in France were analyzed.
View Article and Find Full Text PDFBackground: Spatial inequalities in cancer management have been evidenced by studies reporting lower quality of care or/and lower survival for patients living in remote or socially deprived areas. NETSARC+ is a national reference network implemented to improve the outcome of sarcoma patients in France since 2010, providing remote access to specialized diagnosis and Multidisciplinary Tumour Board (MTB). The IGéAS research program aims to assess the potential of this innovative organization, with remote management of cancers including rare tumours, to go through geographical barriers usually impeding the optimal management of cancer patients.
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