Exploring limits for data registration in the context of PROCARE, a quality improvement project on rectal cancer.

Background: A high burden of registration in the context of quality improvement projects may result in registration fatigue.

Methods: Time required for data collection and registration was measured. Quality of care indicators (QCI) were scored and factors for adjusted benchmarking were identified.

Comparison of the effects of aprotinin and tranexamic acid on blood loss and red blood cell transfusion requirements during the late stages of liver transplantation.

Background: During liver transplantation (LT), profound activation of the fibrinolytic system can contribute significantly to perioperative bleeding. Prophylactic administration of antifibrinolytic agents has been shown to reduce blood loss and the need for allogeneic transfusion in these conditions.

Study Design And Methods: This prospective randomized trial included 51 cirrhotic patients undergoing LT.