Double drape tectonic patch with cyanoacrylate glue for surgical repair of corneal defects: 8 cases.

Objective: To describe the use of a double drape tectonic patch with cyanoacrylate glue technique for the treatment of deep or penetrating corneal defects in cats and dogs.

Animals Studied: Eight client-owned animals of which five were cats and three were dogs.

Procedure: Eight cases: Four with descemetoceles, three with corneal perforations, and one with a deep stromal ulcer were treated with a double layer of plastic drape material adhered to the cornea with a cyanoacrylate (2-octyl or 2-octyl, N-butyl)-based tissue adhesive.

Punctal stenosis in 6 dogs following the long-term use of topical neomycin-polymyxin B-dexamethasone.

Six dogs were diagnosed with punctal stenosis following the long-term use of topical neomycin-polymyxin B-dexamethasone (NPD). All patients were initially presented for ophthalmic diseases requiring ongoing anti-inflammatory therapy. Five of the 6 dogs had previously or concurrently been treated with topical anti-inflammatory medications other than NPD.

Comparison of the efficacy of various concentrations and combinations of serum, ethylenediaminetetraacetic acid, tetracycline, doxycycline, minocycline, and N-acetylcysteine for inhibition of collagenase activity in an in vitro corneal degradation model.

OBJECTIVE To compare the efficacy of various concentrations and combinations of serum, EDTA, 3 tetracyclines, and N-acetylcysteine (NAC) for collagenase inhibition in an in vitro corneal degradation model. SAMPLE Grossly normal corneas from recently euthanized dogs and horses and fresh serum from healthy dogs and horses. PROCEDURES Serum was pooled by species for in vitro use.

Canine panuveitis: a retrospective evaluation of 55 cases (2000-2015).

Objective: To determine the most common etiologies of panuveitis in a group of dogs, patient response to therapy, and visual outcome.

Design: Retrospective study.

Materials And Methods: Medical records of 55 dogs diagnosed with panuveitis at the Purdue University Veterinary Teaching Hospital between December 2000 and December 2015 were reviewed.

Eye examination in the cat: Step-by-step approach and common findings.

Practical Relevance: The ability to perform a complete eye examination in the cat is critically important for patients with an ocular disorder or a systemic disease, as well as for the geriatric cat.

Clinical Challenges: Cats may need short breaks between portions of the eye exam in order to minimize stress. For the clinician, use of ophthalmic equipment and interpretation of normal vs abnormal findings may take some practice in order to develop proficiency.

Comparison of the in vitro anticollagenase efficacy of homologous serum and plasma on degradation of corneas of cats, dogs, and horses.

OBJECTIVE To compare the anticollagenase efficacy of fresh feline, canine, and equine serum and plasma on in vitro corneal degradation. SAMPLE Grossly normal corneas from recently euthanized dogs, cats, and horses and fresh serum and plasma from healthy dogs, cats, and horses. PROCEDURES Serum and plasma were pooled by species and used for in vitro experiments.

Use of an ophthalmic formulation of megestrol acetate for the treatment of eosinophilic keratitis in cats.

Objective: To evaluate a compounded ophthalmic formulation of 0.5% megestrol acetate to treat eosinophilic keratitis in cats.

Study Design: Prospective study.

Evaluation of species differences and the effects of storage duration and temperature on the anticollagenase efficacy of canine, feline, and equine serum on in vitro corneal degradation.

OBJECTIVE To evaluate species differences and effects of storage duration and temperature on the anticollagenase efficacy of canine, feline, and equine serum on in vitro corneal degradation. SAMPLES Corneas and serum from dogs, cats, and horses. PROCEDURES Clinically normal corneas from dogs, cats, and horses were harvested within 2 hours after euthanasia.

Comparison of ultrasound biomicroscopy and standard ocular ultrasonography for detection of canine uveal cysts.

Objective: To compare ultrasound biomicroscopy (UBM) with standard ocular ultrasonography for detection of canine uveal cysts and to determine the sensitivity, specificity, and interobserver agreement for detection of uveal cysts with UBM.

Sample: 202 enucleated eyes from 101 dogs.

Procedures: 2 examiners examined 202 eyes by means of UBM (50 MHz) to identify uveal cysts.

Ocular manifestations of feline viral diseases.

Feline viral diseases are common and cats can be presented with a variety of clinical manifestations. Ocular disease associated with viral pathogens is not unusual, particularly with viruses causing upper respiratory tract disease in cats, such as feline herpesvirus type 1 and feline calicivirus. These agents mainly cause ocular surface disease.

Prevalence of methicillin-resistant Staphylococcus spp. in the conjunctival sac of healthy dogs.

Objectives: To determine the prevalence of selected coagulase-positive methicillin-resistant Staphylococcus aureus (MRS) in the conjunctival sac in a group of healthy dogs and to compare the prevalence of ocular MRS colonization with colonization of typically assessed body sites including the nasal cavity and rectum.

Animals Studied: 123 healthy dogs were used in the prevalence study: 40 dogs from a shelter and 83 privately owned dogs.

Procedures: The sampling procedure included culturing three separate sites per subject in the following order: the lower conjunctival fornices, the nares, and rectum.

Effects of topical ocular administration of high doses of human recombinant interferon alpha-2b and feline recombinant interferon omega on naturally occurring viral keratoconjunctivitis in cats.

Objective: To determine whether 14-day topical ocular administration of high doses of feline recombinant interferon omega (FelFN) or human recombinant interferon alpha-2b (HulFN) solution improves clinical disease and decreases virus shedding in cats with naturally acquired viral keratoconjunctivitis.

Animals: 36 cats with upper respiratory tract disease and ocular involvement.

Procedures: Cats received 1 drop of FelFN solution (1 × 10(6) U/mL), HulFN solution (1 × 10(6) U/mL), or saline (0.

Septic lens implantation syndrome in a cat.

A 13-year-old female spayed domestic shorthair cat was presented initially for a change in the appearance of the left eye. On initial examination, a small penetrating wound was suspected as the cause for a corneal scar, an anterior cortical incipient cataract and mild iritis. The cat was not re-presented until 1 year later at which time ocular pain was marked.

Bartonellosis in cats: a role in uveitis?

Bartonellosis has been widely studied in human and veterinary medicine over the past two decades. Despite this fact, it remains an enigmatic disease in many ways. The causative bacteria, Bartonella spp, are transmitted to cats by fleas and thus the prevalence in cat populations, particularly in temperate climates, is high.

Evaluation of four drugs for inhibition of paracentesis-induced blood-aqueous humor barrier breakdown in cats.

Objective: To compare inhibitory effects of topically applied 1% prednisolone acetate suspension, 0.03% flurbiprofen solution, 0.1% dexamethasone suspension, and 0.

Effect of eyelid manipulation and manual jugular compression on intraocular pressure measurement in dogs.

Objective: To determine the effect of eyelid manipulation and manual jugular compression on intraocular pressure (IOP) measurement in clinically normal dogs.

Design: Randomized clinical trial.

Animals: 30 dogs (57 eyes) without diseases or medications that affect IOP.

Postoperative complications and visual outcomes of phacoemulsification in 103 dogs (179 eyes): 2006-2008.

Objective: To describe the postoperative complications and visual outcome after phacoemulsification in dogs and identify risk factors for complications.

Animals Studied: One hundred and three dogs (179 eyes) that had phacoemulsification with or without intraocular lens (IOL) placement including foldable acrylic IOLs between March 2006 and March 2008 at Purdue University Veterinary Teaching Hospital.

Procedure: Medical records were reviewed and occurrence and dates of postoperative complications were tabulated.

Stability of 0.5% cidofovir stored under various conditions for up to 6 months.

Objective: To evaluate the effect of time, temperature and storage vial material on the antiviral activity of 0.5% cidofovir solution.

Procedures: Commercial 7.

Coccidioides posadasii keratouveitis in a llama (Lama glama).

A 7-year-old male llama was examined for a 3-month history of weight loss, and unilateral keratouveitis. Clinical examination revealed nonulcerative corneal stromal abscessation, corneal vascularization, corneal edema, miosis, posterior synechia, cataract, and fibrin in the anterior chamber of the right eye. The left eye was normal.

Heterologous penetrating keratoplasty for treatment of a corneal sequestrum in a cat.

A corneal sequestrum was diagnosed in an 8-year-old, neutered male Burmese cat. A heterologous penetrating keratoplasty (PK) (fresh canine corneal tissue) was performed to restore a clear visual axis. A heterograft was selected in order to decrease the risk of viral transmission as a screened donor was not available.

Results of diagnostic ophthalmic testing in healthy guinea pigs.

OBJECTIVE-To report values for tear production, central corneal touch threshold (CTT), and intraocular pressure (IOP) in healthy guinea pigs and determine results of aerobic bacterial culture and cytologic examination of conjunctival swab specimens. DESIGN-Cross-sectional study. ANIMALS-31 Healthy guinea pigs (62 eyes) of various ages and breeds.

Effects of lambda-carrageenan on in vitro replication of feline herpesvirus and on experimentally induced herpetic conjunctivitis in cats.

Purpose: To evaluate the inhibitory effect of lambda-carrageenan type IV on feline herpesvirus (FHV)-1 in an in vitro model and in experimentally induced conjunctivitis in vaccinated cats.

Methods: Standard plaque reduction assay, virus titration, and quantitative polymerase chain reaction (qPCR) were used to assess the effect of carrageenan on FHV-1 in vitro. Eighteen adult specific pathogen-free cats, vaccinated against FHV-1 several months earlier, were used to determine the ocular irritative effects of carrageenan, followed by the effect on FHV-1-induced conjunctivitis.

Ocular melanocytic neoplasia.

Tumors of melanocytic origin in ocular tissues are relatively uncommon in dogs and cats, and although many are benign, some have a high potential for metastasis. In addition, even small ocular masses can be significant due to their potential vision-threatening sequelae. Such tumors may occur on the eyelids, on the conjunctival surface, along the limbus, or within the uveal tract.