Publications by authors named "Jean Selim"

Article Synopsis
  • The study aimed to evaluate the effectiveness of two indicators, pulmonary artery pulse pressure indexed (PAPi) and radial artery pulse pressure (rPP), in predicting the success of weaning patients off venoarterial extracorporeal membrane oxygenation (VA-ECMO) used for cardiogenic shock.
  • Conducted as a retrospective cohort study at a single tertiary hospital, researchers analyzed data from patients who received VA-ECMO between 2017 and 2021 and explored the relation between these pressures and weaning outcomes.
  • Results showed that higher values of PAPi and rPP were significantly correlated with successful weaning, indicating that these measurements could serve as reliable predictors for clinicians managing VA-ECMO patients.
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Objective: Bleeding after cardiac surgery leads to poor outcomes. The objective of the study was to build the PeriOperative Bleeding Score in Cardiac surgery (POBS-Card) to predict bleeding after cardiac surgery.

Methods: We conducted a retrospective cohort study in 2 academic hospitals (2016-2019).

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Article Synopsis
  • - The study aimed to investigate whether the preoperative Leicester Cough Questionnaire (LCQ) can predict postoperative complications after major lung surgery for non-small cell lung cancer (NSCLC).
  • - Conducted at Rouen University Hospital, the retrospective cohort study included 71 patients, finding that 27.1% experienced significant postoperative complications, but the LCQ's predictive value was marginal (ROC curve area of 0.60).
  • - The researchers concluded that the LCQ was not a reliable predictor of complications, citing the need for larger studies to confirm findings due to insufficient statistical precision.
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Article Synopsis
  • * Immune checkpoint inhibitors and targeted therapies have transformed treatment for NSCLC, offering better outcomes than traditional chemotherapy, although issues with acquired resistance remain.
  • * Thoracic surgery has improved through minimally invasive techniques and precision surgery, emphasizing comprehensive patient care from pre-operative support through post-treatment follow-up and potential salvage surgery options.
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Background: With the generalization of social network use by health care workers, we observe the emergence of breaches in medical confidentiality. Our objective was to determine, among anesthesiology and intensive care health care workers, the rate of medical confidentiality breaches among professional tweets.

Methods: We performed a retrospective analysis of public Twitter data available through the official Twitter application program interface.

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Introduction: The prevention of respiratory complications is a major issue after thoracic surgery for lung cancer, and requires adequate post-operative pain management. The erector spinae plane block (ESPB) may decrease post-operative pain. The objective of this study was to evaluate the impact of ESPB on pain after video or robot-assisted thoracic surgery (VATS or RATS).

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Objectives: Adequate pain management after thoracoscopic surgery is a major issue in the prevention of respiratory complications. The combination of the paravertebral block (PVB) with the serratus anterior plane block (SAPB) may decrease postoperative pain. The objective of this study was to evaluate the impact of the combination of PVB and SAPB on the consumption of morphine and pain after video- or robot-assisted thoracic surgery.

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Background: Postoperative pain after cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS-HIPEC) is important. It appears essential to reduce postoperative pain and morphine consumption.

Methods: Retrospective study in a university hospital comparing patient benefiting from CRS-HIPEC under opioid-free anesthesia (OFA; dexmedetomidine) to those anesthetized with opioid anesthesia (OA; remifentanil) using a propensity score matching method.

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Background: Many studies explored the impact of ventilation during cardiopulmonary bypass (CPB) period with conflicting results. Functional residual capacity or End Expiratory Lung Volume (EELV) may be disturbed after cardiac surgery but the specific effects of CPB have not been studied. Our objective was to compare the effect of two ventilation strategies during CPB on EELV.

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Maxillofacial trauma is still very common in France with possible involvement of all face bones. Outpatient surgery is an axis strongly put forward by the public authorities. The aim of this study is to establish a current state in the outpatient management of facial fractures in France in 2019 before COVID infection.

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Background: The most frequent complication observed after ambulatory surgery is acute postoperative pain.

Objective: The purpose of this study was to evaluate the late incidence of postoperative pain at 7 days after day surgery.

Methods: We retrospectively included patients who underwent day surgery under general or regional anesthesia and those who underwent local anesthesia in Rouen University Hospital from January 2018 to February 2020.

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The routine use of mechanical circulatory support during lung transplantation (LTx) is still controversial. The use of prophylactic human albumin (HA) or hypertonic sodium lactate (HSL) prime in mechanical circulatory support during LTx could prevent ischemia−reperfusion (IR) injuries and pulmonary endothelial dysfunction and thus prevent the development of pulmonary graft dysfunction. The objective was to investigate the impact of cardiopulmonary bypass (CPB) priming with HA and HSL compared to a CPB prime with Gelofusine (GF) on pulmonary endothelial dysfunction in a lung IR rat model.

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Background: Although the presence of medical societies on social networks (SNs) could be interesting for disseminating professional information, there is no study investigating their presence on SNs.

Objective: The aim of this viewpoint is to describe the worldwide presence and activity of national anesthesia societies on SNs.

Methods: This observational study assessed the active presence (≥1 post in the year preceding the collection date) of the World Federation of Societies of Anesthesiologists member societies on the SNs Twitter, Facebook, Instagram, and YouTube.

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Background: The Minto pharmacokinetic model is used for target-controlled infusion of remifentanil. The reliability of this model has never been evaluated during normothermic cardiac surgery with cardiopulmonary bypass (CPB). The aim of this study was to assess the predictive performance of the model during CPB to determine its reliability during cardiac surgery.

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Background: Nowadays, video-assisted thoracoscopic surgery (VATS) and robotic-assisted thoracoscopic surgery (RATS) are known to be safe and efficient surgical procedures to treat early-stage non-small cell lung cancer (NSCLC). We assessed whether RATS increased disease-free survival (DFS) compared with VATS for lobectomy and segmentectomy.

Methods: This retrospective cohort study included patients treated for resectable NSCLC performed by RATS or VATS, in our tertiary care center from 2012 to 2019.

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Introduction: Anesthesia remains a young medical discipline still relatively unknown by the general public and probably by some health professionals. The objective of the study was to evaluate the perception of anesthesiologist by health professionals working with this specialty.

Methods: We distributed a computerized survey to physicians, residents, paramedical, midwives, and administrative staff in different hospitals between April and July 2018 in Normandy, France.

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Questions: How well do the 6-minute stepper test (6MST) and sit-to-stand test (STST) predict complications after minimally invasive lung cancer resection? Do the 6MST and STST provide supplementary information on the risk of postoperative complications in addition to the prognostic variables that are currently used, such as age and the American Society of Anesthesiology (ASA) score?

Design: Prospective inception cohort study with follow-up for 90 days.

Participants: Consecutive sample of adults undergoing major lung resection with video-assisted thoracic surgery (VATS) or robot-assisted thoracic surgery (RATS).

Outcome Measures: Patients had a preoperative functional evaluation with the 6MST and STST.

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Mainly constituted of glycosaminoglycans and proteoglycans, the glycocalyx is anchored in the plasma membrane, covering, in particular, the extracellular face of the arterial endothelium. Due to its complex three-dimensional (3D) architecture, the glycocalyx interacts with a wide variety of proteins, contributing to vascular permeability, the flow of mechanotransduction, and the modulation of local inflammatory processes. Alterations of glycocalyx structure mediate the endothelial dysfunction and contribute to the aggravation of peripheral vascular diseases.

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Background: Thrombosis is frequent during COVID-19 disease, and thus, identifying predictive factors of hemostasis associated with a poor prognosis is of interest. The objective was to explore coagulation disorders as early predictors of worsening critical conditions in the intensive care unit (ICU) using routine and more advanced explorations.

Materials: Blood samples within 24 h of ICU admission for viscoelastic point-of-care testing, (VET), advanced laboratory tests: absolute immature platelet count (A-IPC), von Willebrand-GPIb activity (vWF-GpIb), prothrombin fragments 1 + 2 (F1 + 2), and the thrombin generation assay (TGA) were used.

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