[Mortality risk factors for upper gastrointestinal bleeding at Brazzville university hospital].

In the absence of interventional endoscopy the treatment of upper digestive hemorrhage a the brazzaville university hospital is only medicinal. Objective of this work was to identify risk factors for upper gastrointestinal bleeding by conducting a retrospective case-type study conducted over a period of 2 years. The 180 patients included for upper digestive hemorrhage were divided into 2 groups accordind to their progressive modality : deceaded patients (cases) and non-deceased patients (controls).

[Clandestine abortion complications and street drugs in Brazzaville].

Introduction: clandestine abortions increase maternal morbi-mortality in sub-Saharan Africa and are closely linked to restrictive legislation and low contraceptive prevalence. In Brazzaville street drugs are commonly used to induce abortion. The purpose of this study is to determine street drug prevalence and socio-demographic characteristics of these patients.

Molecular characterization of hepatitis B virus among chronic hepatitis B patients from Pointe Noire, Republic of Congo.

Background: Chronic Hepatitis B infection is a major health problem in Republic of Congo therefore molecular analysis of HBV strains is important to detect the patients at high risk of disease progression.

Methods: Serum samples were obtained from 111 chronic HBV patients in Pointe Noire. HBsAg, HBeAg and HBeAb were detected.

Molecular Detection of Helicobacter pylori and its Antimicrobial Resistance in Brazzaville, Congo.

Back Ground: Helicobacter pylori infection is involved in several gastroduodenal diseases which can be cured by antimicrobial treatment. The aim of this study was to determine the prevalence of H. pylori infection and its bacterial resistance to clarithromycin, fluoroquinolones, and tetracycline in Brazzaville, Congo, by using molecular methods.

Higher levels of hepatitis C virus RNA found in blood donors co-infected with HIV as compared to HCV mono-infected donors.

Introduction: Hepatitis C virus (HCV) infection and human immunodeficiency virus (HIV) infections are public health problems in sub-Saharan countries such as the Republic of Congo. HIV infection could impact the characteristics of HCV infection in co-infected people. We investigated HCV-HIV co-infection among blood donors in Congo.

Reduction of multiplicity of infections but no change in msp2 genetic diversity in Plasmodium falciparum isolates from Congolese children after introduction of artemisinin-combination therapy.

Background: In this first study conducted after the introduction of artemisinin-combination therapy (ACT), the major objective was to evaluate Plasmodium falciparum genetic diversity and multiplicity of infection in isolates from Congolese children between one and nine years of age enrolled and followed up for one year. The secondary objective was to characterize the msp2 profiles of P. falciparum isolates collected from successive malaria episodes in ten children who had four or more clinical episodes during the follow up.

Helicobacter pylori infection is identified as a cardiovascular risk factor in Central Africans.

Background: Helicobacter pylori is now incriminated in the pathogenesis of atherosclerosis.

Objective: To examine the importance of H. pylori infection as a cardiovascular disease (CVD) risk factor.

[Eosinophilic gastroenteritis in a tropical area: report of a Congolese case].

Eosinophilic gastroenteritis is an uncommon disease with an unknown natural history, and its relation to digestive allergies has not been confirmed. This study reports the case of a 27 year old patient who developed eosinophilic gastroenteritis with gastric, intestinal, rectal and peritoneal localisations. In the Congo, massive blood hypereosinophilia suggests digestive parasitosis and gastroenteritis with malnutrition and cutaneous symptoms suggest AIDS/HIV, making the present agnosis uncommon.