Publications by authors named "Jean Pierre Schuster"

Introduction: Major depressive disorder (MDD) exhibits heterogeneity in treatment response.

Objective: This exploratory analysis aims to evaluate the differential changes in individual items of the MADRS between melancholic MDD (M-MDD) and unspecified MDD (U-MDD) following electroconvulsive therapy (ECT).

Methods: The study included 23 patients with unipolar MDD who received ECT.

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Article Synopsis
  • Electroconvulsive therapy (ECT) is an effective treatment for depression in elderly patients, but its role in the treatment sequence is not well-defined.
  • A review of 19 studies found no significant links between various biological factors (like cortisol levels and brain atrophy) and treatment response, while certain conditions (like elevated CRP and S100B levels) may indicate better outcomes.
  • The need for further research on ECT in the elderly is emphasized, as the current studies are limited, but incorporating new findings could lead to more personalized treatment strategies.
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The aim of this study is to describe the patterns of prescription of benzodiazepine-receptor agonists in hospitalised patients in four psychogeriatric units in Switzerland. This is a retrospective cross-sectional study that included patients aged 65 years or more hospitalised in one of the four psychogeriatric units of a university hospital in Switzerland during 2019. The presence, type and dose of benzodiazepine-receptor agonists was assessed at admission and at discharge.

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Resistance to treatment in psychiatry can arise from a variety of causes, and here we look at two strategies that can improve this problem. First, we discuss the role of patients' relatives; in addition to family therapy interventions, setting up groups of relatives makes it possible to increase their skills in helping their sick relative and to help each other in this process. And finally, we look at the option of interventional psychiatry.

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Agitation is a common feature in people with dementia. Agitation can be the clinical expression of a medical condition comorbid with dementia or a behavioural and psychological symptom of dementia. In both cases, it is a clinical manifestation and not a disease in itself.

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  • The study investigates how clinical factors influence the onset timing of major depression across different age groups in a US adult sample.
  • Compared to those whose first major depressive episode (MDE) occurs between 18-34 years, earlier MDE (under 18) is linked to more childhood maltreatment and family psychiatric history, while later onset (60+) is tied to widowhood and prior anxiety disorders.
  • The findings highlight the importance of age-specific risk factors, suggesting that enhancing early detection and prevention strategies could significantly decrease the overall impact of MDE.
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Purpose: There is a substantial gap between people having a mental disorder and those treated for this disorder. Studies that assessed the influence of age on healthcare use for major depressive disorder (MDD) have provided inconsistent results. We aimed to assess healthcare use in terms of treatment-seeking and psychotropic medication use in four age groups of 45- to 85-year-old community dwellers meeting criteria for MDD.

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Recommendations for the Diagnosis and Therapy of Psychotic Disorders in the Elderly Psychotic disorders in the elderly cover a wide range of causes and manifestations. They often occur as part of a depression, dementia, substance abuse or delirium. While psychosis can occur with a first manifestation in advanced age, many patients with chronic psychotic disorders reach a high age.

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In accommodation facilities for dependent elderly, entertainment is found in various forms. It is the place that promotes the stability and development of the relational, social and cultural life of the residents. Listening to what is said and experienced during the sessions allows a useful representation of the movements within the establishment.

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  • This systematic review aims to investigate at-risk alcohol use and related health issues among older adults living independently, as there is currently limited epidemiological data on this topic.
  • The researchers will search multiple databases for studies on alcohol consumption, comorbidities, and measurement tools, with a focus on understanding the relationship between alcohol use and health in older populations.
  • Results will be shared in conferences and published in peer-reviewed journals, without the need for ethical approval for the study.
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Objectives: Despite evidence of low representativeness of clinical trial results for depression in adults, the generalizability of clinical trial results for late-life depression is unknown. This study sought to quantify the representativeness of pharmacologic and psychotherapy clinical trial results for late-life unipolar depression.

Method: Data were derived from the 2004-2005 National Epidemiologic Survey on Alcohol and Related Conditions (NESARC), a nationally representative sample of 34,653 adults from the United States population.

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  • The study investigates the prevalence and clinical factors related to benzodiazepine use among older patients (55+) with schizophrenia spectrum disorder, finding a notable usage rate of 29.8%.
  • Older patients prescribed benzodiazepines were often more likely to have additional medical issues, cognitive impairments, and a history of suicide attempts, suggesting a correlation with higher vulnerability.
  • The findings indicate that benzodiazepine use might be associated with a more challenging treatment population rather than indicating a direct link to schizophrenia severity.
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The limited published literature on the subject suggests that there may be differences in how females and males experience narcissistic personality disorder (NPD) symptoms. The aim of this study was to use methods based on item response theory to examine whether, when equating for levels of NPD symptom severity, there are sex differences in the likelihood of reporting DSM-IV-TR NPD symptoms. We conducted these analyses using a large, nationally representative sample from the USA (n=34,653), the second wave of the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC).

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Telemedicine has recently been developed in response to epidemiological, demographical and economical problems in the French Health care system. Telepsychiatry appears to be a suitable tool, but few studies have evaluated its applicability and acceptability when applied to the elderly. The use of such a tool is interesting because elderly people have many psychiatric disorders, but encounter many difficulties to access health care.

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Objective: Previous studies have suggested a positive effect of retirement on depressive symptoms. The present study took advantage of the large-scale, prospective Gaz et Electricité (GAZEL) cohort to examine whether personality could influence this effect.

Methods: Depressive symptoms were assessed in 1993, 1996, 1999, 2002, 2005, and 2008 with the Center for Epidemiologic Studies Depression Scale (CES-D).

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Objective: Evidence for an association between hostility and peptic ulcer mainly relies on cross-sectional studies. Prospective studies are rare and have not used a validated measure of hostility. This prospective study aimed to examine the association between hostility and peptic ulcer in the large-scale French GAZEL cohort.

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Objectives: This study sought to determine the clinical and sociodemographic correlates and the treatment-seeking rate of major depressive disorder (MDD), diagnosed according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, among older adults and its association with comorbid psychiatric disorders and perceived health status.

Methods: Data were drawn from the 2001-2002 National Epidemiologic Survey on Alcohol and Related Conditions, a large cross-sectional survey (N = 43,093) representative of the US population.

Results: Compared with participants aged 65 years and older without a 12-month diagnosis of MDD, those with MDD were more likely to have lifetime and 12-month comorbid psychiatric disorders.

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Article Synopsis
  • The aging population is increasing due to longer life expectancy, creating a greater demand for healthcare services tailored to their needs, especially regarding mental health issues like depression.
  • About 20% of elderly residents in public facilities suffer from major depressive episodes, leading to higher risks of suicide and reduced quality of life.
  • There is a need to improve physicians' skills in recognizing and treating depression in older adults, as well as to create specialized psychiatric wards in hospitals and nursing homes to better support this vulnerable group.
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  • - The study aimed to investigate the prevalence and impact of personality disorders among adults aged 65 and older, including their sociodemographic factors and comorbid conditions.
  • - Data from the National Epidemiologic Survey revealed that 8.07% of older adults had at least one personality disorder, with obsessive-compulsive personality disorder being the most common, and these individuals experienced a lower quality of life.
  • - The research highlights a strong link between personality disorders and various disabilities and medical/psychiatric issues in older adults, suggesting a need for improved prevention and intervention strategies for this age group.
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  • * Using data from a large national survey, the researchers compared the rates of pure MDD and MDD plus subthreshold hypomania across different age groups.
  • * The results indicate that older adults have significantly lower prevalence of subthreshold hypomania, while their rates of pure MDD are similar to those of younger adults, suggesting that medical conditions may also play a role in older individuals experiencing depression.
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