Publications by authors named "Jean Pierre Saint-Maurice"

Purpose: The purpose of this study was to identify potential association between transverse sinus stenosis (TSS) and temporal bone thinning downstream of TSS on computed tomography (CT).

Materials And Methods: Clinical and radiological data of patients with venous pulsatile tinnitus due to TSS (TSS group) and treated with stenting from 2019 to 2022 were retrospectively collected. An age-matched control group of patients with venous or neutral pulsatile tinnitus (control group) was built.

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Background And Purpose: Lateral sinus stenosis is the most common cause of venous pulsatile tinnitus (VPT). Stenting is an effective treatment after demonstration of a trans-stenotic pressure gradient; however, pressure measurement has many technical limitations. In 2018, a study showed that a combined approach with intravascular velocity measurement could be effective in identifying most appropriate candidates for stenting.

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The rabbit VX2 is a large animal model of cancer used for decades by interventional radiologists to demonstrate the efficacy of various locoregional treatments against liver tumors. What do we know about this tumor in the new era of targeted therapy and immune-oncology? The present paper describes the current knowledge on the clinics, biology, histopathology, and tumor microenvironment of VX2 based on a literature review of 741 publications in the liver and in other organs. It reveals the resemblance with human cancer (anatomy, vascularity, angiogenic profile, drug sensitivity, immune microenvironment), the differences (etiology, growth rate, histology), and the questions still poorly explored (serum and tissue biomarkers, genomic alterations, immune checkpoint inhibitors efficacy).

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Background: The natural history of unruptured intracranial aneurysms (UIAs) in Western populations is still debated, especially for those <7 mm. Reporting data of a large single-center cohort managed with watchful waiting is therefore interesting.

Methods: From January 2011 to June 2019, 662 UIAs were followed up by yearly MR angiography.

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Article Synopsis
  • The study looked at a new way to protect sinuses during a procedure for patients with certain types of blood vessel issues in the brain.
  • They used a temporary stent to keep the sinuses open while treating the condition, and it worked well for the patients in the study.
  • No problems happened during the procedures, and the patients felt better afterwards, but more research is needed to make sure it's really safe for everyone.
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  • Endovascular treatment (EVT) is a way to treat dangerous brain problems called infectious intracranial aneurysms (IIAs) that can happen with heart infections.
  • A study looked at 31 patients who had 62 IIAs treated with EVT between 2009 and 2020, and most didn't have any serious problems afterward.
  • The results showed that EVT worked well to stop these brain issues from getting worse, and there were no major risks for the patients during or after surgery.
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Dural sinus stenting is an increasingly recognized intervention for the treatment of lateral sinus stenosis. This procedure can be challenging in tortuous anatomy and in the presence of intraluminal septa because of poor trackability and crossability of long sheath commonly used for stenting. We report a technique using a pilot angioplasty balloon positioned at the distal end of the long sheath that improves its navigability in dural sinuses and facilitated the intervention.

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Objective: Intracranial dural arteriovenous fistula (DAVF) is mainly treated with an endovascular approach. Two major treatment advances include transvenous embolization (TVE) with coils in 1989 and, more recently, transarterial embolization with Onyx. The aim of this study was to present a large monocentric series of patients with DAVF treated with TVE.

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Objective: Preoperative embolization of juvenile nasopharyngeal angiofibroma (JNA) is usually performed by the occlusion of branches of the external carotid artery (ECA). However, a significant proportion of JNAs also receive blood from the internal carotid artery (ICA). The objective of this study was to report on the feasibility and clinical impact of superselective embolization of ICA branches in complex cases of JNA.

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Background: A significant proportion of spontaneous cerebrospinal fluid (sCSF) leaks are associated with idiopathic intracranial hypertension (IIH). The aim of this study was to assess the association between sCSF rhinorrhea and transverse venous sinus stenosis (VSS), a feature commonly observed in IIH with a proposed role in its pathophysiology.

Methods: In this single-center, retrospective, matched case-control study, venous and pituitary imaging data of consecutive patients undergoing endoscopic surgery for sCSF rhinorrhea over the last 10 years were retrospectively reviewed.

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Background: Whether carotid artery web can be considered as a potential source of arterial thromboembolism in ischemic stroke remains uncertain.

Aims: In a large sample of individuals with large intracranial artery occlusion, we compared the prevalence of carotid artery webs between patients with and without embolic stroke of undetermined source.

Methods: In a single-center study of consecutive patients with anterior circulation ischemic stroke referred for mechanical thrombectomy, the presence of carotid artery web was systematically assessed by two independent readers.

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Article Synopsis
  • The study explores the anatomical origins of the middle meningeal artery (MMA) in patients with chronic subdural hematoma (CSDH), noting the possible complications of embolization treatment when MMA stems from the ophthalmic artery.
  • It reviewed data from 42 patients with CSDH and found that 13.8% had their MMA originating from the ophthalmic artery, compared to only 0.7% in a control group undergoing treatment for a different condition.
  • The findings suggest a need for careful pre-procedural assessment to identify this variant in CSDH patients, as it can affect the feasibility of safe embolization treatment.
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Background: Whether delayed cerebral infarction (DCIn) after aneurysmal subarachnoid hemorrhage (aSAH) is driven by large artery vasospasm is still controversial.

Objective: To study the association between DCIn and vasospasm by using quantitative assessment of vasospasm up to distal arteries with time and territorial-based correlation.

Methods: Clinical and imaging data of 392 patients with aSAH treated at our center between 2012 and 2017 were reviewed.

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Article Synopsis
  • Pelvic and abdominal arteriovenous malformations (AVM) are uncommon but serious vascular conditions that can lead to significant health issues.
  • They can occur on their own (sporadic) or as part of a genetic syndrome, and may cause symptoms due to increased blood flow that can lead to heart failure.
  • The preferred treatment method is endovascular management, which is often part of a team-based approach to care.
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Introduction: Transcranial Doppler (TCD) of the middle cerebral artery (MCA) enables the measurement of the mean blood velocity (MCA) and the estimation of the cerebral blood flow (CBF), provided that no significant changes occur in the MCA diameter (MCA). Previous studies described a decrease in the MCA associated with the induction of total intravenous anesthesia (TIVA) by propofol and remifentanil. This decrease in blood velocity might be interpreted as a decrease in the CBF only where the MCA is not modified across TCD examinations.

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Lateral venous sinus stenoses have been associated with idiopathic intracranial hypertension and venous pulsatile tinnitus. Venous pressure measurement is traditionally performed to assess the indications for stenting in patients with idiopathic intracranial hypertension. However, its reliability has recently been questioned by many authors.

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Objective: To determine long term safety and efficacy of endovascular treatment of spinal cord arteriovenous malformations (AVMs), with calibrated particle embolization as a firstline approach.

Methods: We reviewed clinical and imaging data of consecutive patients who underwent endovascular treatment for both nidal and fistulous type spinal cord AVMs in our center, from 1990 to 2015. Outcome at the last follow-up was assessed by an independent observer.

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Article Synopsis
  • The study aimed to investigate how common and how effectively spontaneous intracranial artery dissection (IAD) is treated during acute ischemic strokes.
  • Researchers reviewed patient data from a thrombectomy center and found IAD in 3% of patients, often linked to previous extracranial dissections.
  • The findings suggest that stenting is an effective treatment, improving recanalization rates and potentially lowering the chance of stroke recurrence, but more research is needed to confirm stenting as a first-line treatment.
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Background: Lateral sinus stenosis is a little-known cause for pulsatile tinnitus (PT). In several small series, stenting has been described as an effective treatment for disabling PT linked with this type of stenosis.

Objectives: To describe the clinical, radiological, and manometric characteristics of patients treated for disabling PT by lateral sinus stenosis.

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Purpose: To analyze the angiographic and clinical results of transarterial embolization with Onyx (Medtronic-Covidien, Irvine, CA) in dural arteriovenous fistulas (DAVFs) partially fed by arteries arising from the carotid siphon or the vertebral arteries.

Methods: We isolated 40 DAVFs supplied by either the tentorial artery of the internal carotid artery (ICA) or the posterior meningeal artery of the vertebral artery. These DAVFs were embolized with Onyx through the middle meningeal artery or the occipital artery.

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Background Investigation of the venous system surrounding a tumor that is invading a dural sinus is of great use for guiding the surgical excision. Non-invasive imaging is often inadequate since enhancement of the tumor causes it to blend with the contrast of the venous vascular structures. Conventional two-dimensional angiography is also often insufficient.

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Background and importance The marginal tentorial artery runs over the free edge of the tentorium. Different origins have been described, always involving branches of the carotid artery. We report the superior cerebellar artery as an unknown origin of this artery.

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Background: Over the past decade, stenting of lateral sinus stenosis has been used to treat idiopathic intracranial hypertension. Two types of stenoses have been identified: extrinsic and intrinsic.

Objective: The aim of this study was to report the results of our use of this procedure to treat patients with extrinsic or intrinsic stenoses in idiopathic intracranial hypertension.

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Introduction: The occurrence of cardiac dysfunction is common after subarachnoid hemorrhage (SAH) and was hypothesized to be related to the release of endogenous catecholamines. The aim of this prospective study was to evaluate the relationship between endogenous catecholamine and cardiac dysfunction at the onset and during the first week after SAH.

Methods: Forty consecutive patients admitted for acute SAH without known heart disease were included.

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Article Synopsis
  • Spinal dural arteriovenous fistulas (AVFs) are the most common spinal arteriovenous malformations, typically treated through microsurgery or endovascular procedures.* -
  • A study of 30 patients treated at a tertiary center between 2001 and 2008 showed that all patients achieved complete cure from a single surgical session without complications.* -
  • After an average follow-up of 32 months, 83% of patients experienced improvement, highlighting the importance of careful patient selection and standardized surgical techniques for successful outcomes.*
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