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Publications by authors named "Jean Pierre Le Couedic"

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Synopsis of recent research by authors named "Jean Pierre Le Couedic"

  • - Jean Pierre Le Couedic's research primarily focuses on myeloproliferative neoplasms (MPNs) and the genetic mutations associated with various hematologic conditions, including essential thrombocythemia and acute myeloid leukemia.
  • - A significant finding from his work includes the identification of atypical mutations in the thrombopoietin receptor (MPL) and their role in myeloproliferative disorders, highlighting the complexity of mutational profiles in patients lacking common mutations like JAK2V617F.
  • - Additionally, Le Couedic has contributed to the understanding of the TET2 gene's role in hematopoietic differentiation, showcasing how its deficiency can impact the differentiation of embryonic stem cells and contribute to myeloid malignancies.

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