Production of high purity Sc from proton irradiation of natural vanadium targets.

Background: Scandium-47 is the therapeutic counterpart to the diagnostic radionuclides, Sc and Sc. Together, these form elementally matched theranostic nuclide pairs, but their incorporation into radiopharmaceuticals requires developing production techniques leading to radioscandium isotopes with high chemical and radionuclidic purity. Previous Sc production methods involved expensive, enriched titanium targets that require additional procedures for target recovery.

Optimized Methods for the Production of High-Purity Pb Using Electroplated Thallium Targets.

Pb is a surrogate imaging match for Pb. This elementally matched pair is emerging as a suitable pair for imaging and targeted radionuclide therapy in cancer care. Because of the half-life (51.

Production of Mn using a semi-automated module.

This work focused on the production and purification of the positron emitter Mn (t = 5.6 d) via the Cr(p,n)Mn reaction, using a TR24 cyclotron and a semi-automated system for the purification of Mn. Based on two-column and three-column systems, the recovery of Mn was 79.

Implementation of Multi-Curie Production of (99m)Tc by Conventional Medical Cyclotrons.

Unlabelled: (99m)Tc is currently produced by an aging fleet of nuclear reactors, which require enriched uranium and generate nuclear waste. We report the development of a comprehensive solution to produce (99m)Tc in sufficient quantities to supply a large urban area using a single medical cyclotron.

Methods: A new target system was designed for (99m)Tc production.