Exploring the therapeutic potential of the oxygenated monoterpene linalool in alleviating saline stress effects on Allium cepa L.

Sodium chloride (NaCl) can cause oxidative stress in plants, which represents a potential obstacle to the development of monocultures worldwide. Onion (Allium cepa L.) is a famous vegetable consumed and used in world cuisine.

Correlations between the degree of infection by wild strain of Toxoplasma gondii in vitro and porcine hematological parameters.

The apicomplexa Toxoplasma gondii is capable of actively proliferating in numerous types of nucleated cells, and therefore has a high potential for dissemination and resistance. Thus, the present work aimed to correlate the inoculum concentrations and amount of post-infection parasites with porcine hematological parameters (including biochemistry) through in vitro culture. Porcine blood was incubated with different concentrations of parasites (1.

Response to carvacrol monoterpene in the emergence of Allium cepa L. seeds exposed to salt stress.

Abiotic stresses including sodium chloride (NaCl) are known to negatively affect plant physiology and seed germination by inducing a delay in establishing seedling emergence. The monoterpene carvacrol is the major component of several aromatic plants and seems to interfere with germination and seedling growth. In this study, we investigated whether treatment with carvacrol attenuates the effects of NaCl on the germination and development of Allium cepa, where biochemical parameters were also analyzed.

Bibliometric analysis of endocrinology, diabetes and metabolism research in South Asia from (2012-2021): Comparison with five developed countries.

Background And Aims: In the present study the research output of the South Asian region (India, Pakistan, Bangladesh, Sri Lanka, Nepal, Maldives, and Bhutan) in endocrinology, diabetes and metabolism (EDM) is highlighted. It was compared with five scientifically advanced countries i.e.

The silver jubilee of the Nitric Oxide journal: From 1997 to 2021.

Based on the Scopus record, Nitric Oxide journal (NOJ) has completed 25 years of publications. On March 8, 2022, the publication data was retrieved from the Scopus database and analyzed on VOSviewer and R-Studio (Bibliometrix R package/Biblioshiny). NOJ has published 1928 research documents majorly comprising of articles (1611/83.

A Potential New Source of Therapeutic Agents for the Treatment of Mucocutaneous Leishmaniasis: The Essential Oil of .

Weeds are an important source of natural products; with promising biological activity. This study investigated the anti-kinetoplastida potential (in vitro) to evaluate the cytotoxicity (in vitro) and antioxidant capacity of the essential oil of (EORe), which is an infesting plant species. The essential oil was analyzed by GC/MS.

Neurolocomotor Behavior and Oxidative Stress Markers of Thiazole and Thiazolidinedione Derivatives against .

Thiazolidine compounds NJ20 {(E)-2-(2-(5-bromo-2-methoxybenzylidene)hydrazinyl)-4-(4-nitrophenyl)thiazole} and NW05 [(2-(benzo (d) (1,3) dioxol-4-ylmethylene)-N-(4-bromophenyl)-thiosemicarbazone] potentiated the effect of norfloxacin in resistant bacteria; however, there are no reports on their effects on in the literature. The objective of this work was to evaluate the behavioral effects and oxidative markers of NW05 and NJ20 in lobster cockroach . To evaluate the behavioral study, a video tracking software was used to evaluate the locomotor points and the exploratory profile of cockroaches in the horizontal and vertical regions of a new environment.

Methylglyoxal disrupts the functionality of rat liver mitochondria.

Methylglyoxal (MG) is a reactive metabolite derived from different physiological pathways. Its production can be harmful to cells via glycation reactions of lipids, DNA, and proteins. But, the effects of MG on mitochondrial functioning and bioenergetic responses are still elusive.

Evaluation of the neuroprotective effect of rutin on Drosophila melanogaster about behavioral and biochemical aspects induced by mercury chloride (HgCl).

Mercury chloride (HgCl) acts as a bioaccumulator capable of causing numerous neurological and physiological changes in organisms in a negative way. However, rutin has been considered a very effective antioxidant compound in the treatment of neurodegenerative diseases, as it can neutralize radicals capable of damaging neuronal cells. In this context, this study aimed to evaluate rutin as a neoprotective agent against the damage induced by HgCl in Drosophila melanogaster.

Sleep Disorders Research From 1945 to 2020: A Bibliometric Analysis.

Background: The objective of the present review is to perform the 1st bibliometric analysis of sleep disorders research.

Methods: The data was retrieved from Scopus in July 2020 for detailed analysis.

Results: The 1st precise document about the sleep disorder was published in 1945.

Toxicological assessment of a bioactive extract from Wedd. seeds using alternative models.

The Wedd. seeds extract has great therapeutic potential due to numerous biological activities such as antioxidant, antibacterial and anti-inflammatory, which are associated with phenolic content. Although this herbal preparation has shown many benefits, recently their toxicity profile has begun to be explored.

Bibliometric Analysis of Current Drug Metabolism: The Twentieth Anniversary from 2000-2019.

Background: Scopus is regularly covering Current Drug Metabolism from 2000 onwards.

Objective: The major objective is to perform the 1st bibliometric analysis of Current Drug Metabolism (CDM).

Methods: The data was retrieved from Scopus in April-May 2020 for detail analysis.

Bibliometric analysis of personalized humanized mouse and Drosophila models for effective combinational therapy in cancer patients.

Research performed using model organisms such as mice and the fruit fly, Drosophila melanogaster has significantly enhanced our knowledge about cancer biology and the fundamental processes of cancer. This is because the major biological properties and genes associated with cancer including signaling pathways, oncogenes, tumor suppressors, and other regulators of cell growth and proliferation are evolutionary conserved. This review provides bibliometric analysis of research productivity, and performance of authors, institutions, countries, and journals associated with personalized animal cancer models, focussing on the role of Drosophila in cancer research, thus highlighting emerging trends in the field.

Research trends in chemico-biological interactions: The golden jubilee (1969-2019).

Since its inception in 1969, Chemico-Biological Interactions (CBI) has persistently published high quality research articles. As part of the journal's golden anniversary (50 years), we performed an electronic search on Scopus to get all publications details. Based on citescore, ranking & percentile, CBI holds 21st position in the top 113 relevant journals (in 2018).

Metabolic aspects of phenolic compounds from seeds in the management of oxidative stress.

Considering the limited number of studies that analyze the behavior of plant preparations in human body, this study aimed to characterize the phenolic compounds from extract (EETg) in terms of antioxidant and metabolic aspects, integrating , and strategies. EETg was analyzed in relation to polyphenols release from the plant matrix under digestion, as well as the pharmacokinetic prediction of their major compounds by simulation and understanding of its antioxidant effect in an alternative animal model. About 35.

In vitro Antibiotic and Modulatory Activity of (L.) Kuntze against strains.

The emergence of fungal resistance to commercial drugs has been a major problem for the WHO. In this context, research with natural products is promising in the discovery of new active substances. Thus, this work evaluated the antifungal effect of a medicinal plant (i.

Reactivity of peptides within the food matrix.

Numerous biological activities have been reported for peptides or peptide-rich fractions from hydrolyzed food proteins. Some of the properties of peptides include antioxidant, antimicrobial, anti-inflammation, antihypertensive, and immune system modulation. To evaluate the efficacy of peptides in vivo, foods have been used as carrier vehicles.

Improvement of mitochondrial function by Tapinanthus globifer (A.Rich.) Tiegh. Against hepatotoxic agent in isolated rat's liver mitochondria.

Ethnopharmacological Relevance: Disturbed mitochondrial function and energy crisis serve as key mechanisms for the development of liver injury. Hence, targeting cellular mitochondria in liver diseases might serve as a therapeutic option. Tapinanthus globifer (A.

Chemical composition and anti-Candida potencial of the extracts of Tarenaya spinosa (Jacq.) Raf. (Cleomaceae).

Phytochemical prospecting was performed by HPLC-DAD. The Inhibitory Concentration of 50% of mortality the microorganisms (IC) was determined and a cell viability curve was obtained. Minimum Fungicidal Concentration (MFC) was determined by subculture in Sabourad Dextrose Agar.

Possible involvement of transcriptional activation of nuclear factor erythroid 2-related factor 2 (Nrf2) in the protective effect of caffeic acid on paraquat-induced oxidative damage in Drosophila melanogaster.

Paraquat (PQ) is a widely used herbicide with no antidote which is implicated in the pathogenesis of the Parkinson's disease. The present study then investigated the potential of caffeic acid (CA), a known antioxidant, cardioprotective and neuroprotective molecule to counteract oxidative stress mediated by PQ. In addition, molecular docking was performed to understand the mechanism underlying the inhibitory effect of CA against PQ poisoning.