Publications by authors named "Jean P Kocher"
J Arthroplasty
November 2020
Article Synopsis
- Pathologic fibrosis involves abnormal gene expression leading to excessive extracellular matrix production, but research on genetic factors in the musculoskeletal (MSK) system is limited.
- A thorough review of studies from 2000 to 2019 revealed that most research on genetic predisposition to fibrosis focused on pulmonary systems, with some on the hands, but very few on the knee.
- Certain genetic variants linked to pulmonary fibrosis also appear in MSK studies, highlighting a need for more investigation into genetic factors affecting fibrosis in other MSK areas, such as the knee and shoulder.
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