Publications by authors named "Jean Michel Clerc"
Background: The real incidence of atrial arrhythmia (AA) after patent foramen ovale (PFO) closure and whether this complication can be prevented remain unknown. We assessed whether flecainide is effective to prevent AA during the first 3 months after PFO closure, and whether 6 months of treatment with flecainide is more effective than 3 months to prevent AA after PFO closure.
Methods: AFLOAT (Assessment of Flecainide to Lower the Patent Foramen Ovale Closure Risk of Atrial Fibrillation or Tachycardia Trial) is a prospective, multicentre, randomized, open-label, superiority trial with a blind evaluation of all the end points (PROBE [Prospective Randomized Open, Blinded End Point] design).
Introduction: Atrial arrhythmia is the most common complication of patent foramen ovale (PFO) closure. The real incidence of post-PFO closure atrial arrhytmia and whether this complication can be prevented is unknown.
Methods/design: The Assessment of Flecainide to Lower the PFO closure risk of Atrial fibrillation or Tachycardia (AFLOAT) trial is a prospective, national, multicentre, randomized, open-label, superiority trial with a blind evaluation of all the endpoints (PROBE design).
Article Synopsis
- This study aimed to compare patient outcomes after undergoing left atrial appendage occlusion (LAAO) versus those who did not have the procedure, focusing on patients with atrial fibrillation (AF) from a national database.
- After matching 1216 patients who received LAAO with 1216 controls, results showed that those with LAAO had significantly lower rates of major clinical events (ischemic stroke, major bleeding, or death) overall, although they had a higher risk of ischemic stroke specifically.
- The findings suggest that while LAAO is effective in reducing the risk of death, it is less effective for stroke prevention, especially in patients with a history of stroke or bleeding issues.
Background: The Amplatzer™ Trevisio™ Intravascular Delivery System (Trevisio DS; Abbott Laboratories, Chicago, IL, USA) facilitates the delivery of Amplatzer™ Occluders and features an ultraflexible tip, which improves assessment of occluder position before release.
Aims: To assess the safety and efficacy of the Trevisio DS for transcatheter closure of patent foramen ovale and atrial septal defect.
Methods: The Amplatzer™ Trevisio™ Intravascular Delivery System Post-Approval Study was a prospective, postmarket, single-arm, multicentre, observational study of the Trevisio DS.
Article Synopsis
- Despite advancements in stent technology, there's still a notable risk of in-stent restenosis (ISR) after procedures like PCI, and comprehensive data on this issue is limited.
- A study analyzed data from the France-PCI registry between 2014 and 2018, focusing on patients with ISR lesions, finding that 7.3% of the patients treated had ISR PCI, mostly involving older individuals with comorbidities like diabetes.
- The results revealed that those undergoing ISR PCI had higher rates of complications after one year compared to non-ISR patients, indicating a need for further research and improved techniques in managing ISR.
Background • Music Care is a smartphone-based application providing a musical intervention for the management of pain and anxiety in a clinical setting. Coronarography is a medical procedure frequently associated with examination anxiety. Objectives • The study intended to perform an initial evaluation of the application for use with patients undergoing a coronarography.
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