Publications by authors named "Jean Medard Kankou"

We report a low (38.7%; p<0.0001) level of IgG seroconversion in patients who were positive for measles virus IgM in the Republic of Congo, despite a history of vaccination.

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  • Measles epidemics are a significant health issue in the Republic of the Congo, despite vaccination efforts targeting children under 5. Between January 2019 and October 2022, 1,330 suspected cases were tested, revealing a 40.3% positivity rate for measles.* -
  • The incidence of confirmed cases increased significantly, from 16.8% in 2019 to 65.9% in 2022, alongside a low overall vaccination rate of 44.8% among children, which correlated with a high positivity rate of 46.6% in that group.* -
  • Risk factors for measles prevalence included female gender, rural living, and geographical risk areas, with
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  • The study investigates a recent outbreak of monkeypox (mpox) in the Republic of the Congo, which emerged after a notable increase in cases in DR Congo since October 2023.
  • Blood, skin, and swabs from suspected mpox cases were collected between January and April 2024, with 31 of 61 samples testing positive for the virus and analyzed using advanced sequencing techniques.
  • The phylogenetic analysis revealed two major clusters of monkeypox virus strains, suggesting connections between the current outbreak and earlier sequences from Central Africa, indicating ongoing transmission dynamics in the region.
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In resource-limited countries, the lack of widespread screening masks the true situation of COVID-19. We conducted this study to assess SARS-CoV-2 spread by detection of specific antibodies and to determine associated factors. A population-based cross-sectional study was conducted.

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Background: Loiasis ( filariasis) is considered a benign disease and is currently not included in the World Health Organization's (WHO's) list of Neglected Tropical Diseases, despite mounting evidence suggesting significant disease burden in endemic areas. We conducted a retrospective cohort study to assess the mortality associated with microfilaremia in the Southwestern Republic of Congo.

Methods: The cohort included 3329 individuals from 53 villages screened for loiasis in 2004.

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In France, around 25% of the estimated number of people living with HIV are migrants, of whom three quarters are from sub-Saharan Africa (SSA). Our objective was to determine factors associated with virological rebound (VR) at the occasion of a transient stay to the country of origin. HIV-positive migrants from SSA participating to the ANRS-VIHVO adherence study between 2006 and 2009, on effective ART with controlled pre-travel HIV-1 plasma viral load (VL), were included.

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