Publications by authors named "Jean Marc Mardirossian"
The disruption of calcium signaling associated with polycystin deficiency has been proposed as the primary event underlying the increased abnormally patterned epithelial cell growth characteristic of Polycystic Kidney Disease. Calcium can be regulated through mechanotransduction, and the mechanosensitive cation channel Piezo1 has been implicated in sensing of intrarenal pressure and in urinary osmoregulation. However, a possible role for PIEZO1 in kidney cystogenesis remains undefined.
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- Acute gastroenteritis is a major health concern, particularly in developing countries like Lebanon, which lacks national surveillance for gastrointestinal infections.
- A one-year multicenter study analyzed 271 samples from patients to identify the prevalence of pathogens causing diarrhea using advanced testing methods.
- Results found that 71% of patients had enteropathogens, with bacterial infections being the most common, highlighting the need for improved surveillance and diagnostic methods in managing these infections effectively.