Publications by authors named "Jean M Malinovsky"
Background: Although poorly studied, chronic postsurgical neuropathic pain (CPNP) represents the second most frequent chronic neuropathic pain etiology, probably affecting 0.5% to 75% of patients with a severe impact on quality of life (QoL). No consensus or treatment algorithm has been elaborated to date, despite a large variety of approaches now available.
View Article and Find Full Text PDFBackground: Neuromuscular blocking agents (NMBAs) are among the leading cause of perioperative anaphylaxis, and most of these reactions are IgE mediated. Allergic sensitisation induced by environmental exposure to other quaternary ammonium-containing compounds, such as pholcodine, has been suggested. The aim of this study was to assess the relationship between pholcodine exposure and NMBA-related anaphylaxis.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates the effectiveness of epinephrine versus arginine vasopressin (AVP) in treating anaphylactic shock (AS) in a rat model, focusing on airway response and arterial pressure.
- Results showed that while both drugs prolonged survival, epinephrine significantly improved arterial pressure and reduced airway obstruction compared to AVP.
- The findings suggest that epinephrine is the preferred treatment for managing airway complications during anaphylactic shock, as it outperformed AVP in restoring normal respiratory function.
Hypersensitivity reactions in the anesthesia setting/allergic reactions to anesthetics.
Curr Opin Allergy Clin Immunol
August 2012
Purpose Of Review: Immediate hypersensitivity reactions are an important cause for mortality and morbidity in anesthesia. The present review considers reports covering epidemiology, diagnosis, and treatment of these reactions.
Recent Findings: Immediate hypersensitivity reactions are largely under-reported, adult women being at significantly higher risk than men.
Background: Vital dyes are widely used for lymphatic mapping and sentinel lymph node biopsy in patients with malignant tumors, and reports of anaphylactic reactions are becoming more frequent.
Objective: Our aims were to describe specific clinical features of hypersensitivity reactions to Patent Blue (Guerbet, Roissy, France), results of the allergy workup, and their consequences for patient management.
Methods: We report a series of 14 clinical cases of dye-induced anaphylaxis recorded between 2004 and 2006 in 4 member centers of a network of French allergoanesthesia outpatient clinics.