Association Between Negative Affectivity and Craving in Substance-Related Disorders: A Systematic Review and Meta-analysis of Direct and Indirect Relationships.

Background: A sizeable literature highlighted that negative affectivity and craving are both known to be implicated in relapses.

Objectives: The present study synthetized the existing litterature to determine strength of the interaction between negative affectivity and craving for substance-related disorders including illicit drugs, alcohol and tobacco.

Methods: We conducted a systematic review in accordance with PRISMA guidelines followed by a meta-analysis.

Emotional dispositions and substance use: mediating effect of alexithymia.

Substance consumption behaviors can range from use to abuse, the latter including addictive behaviors. Relationships between emotionality, alexithymia and substance-consumption behaviors among young adults were investigated through an explanatory model wherein alexithymia fulfills a mediating function by acting as an emotion-adjustment process. 256 students (62.