Publications by authors named "Jean Henri Maselli-Schoueri"

Article Synopsis
  • - Cancer-related fatigue impacts up to 90% of cancer patients and can linger even after treatment, but there is no established treatment, prompting interest in alternatives like natural supplements, specifically guaraná.
  • - A systematic review and meta-analysis, which included 4 articles and 1 abstract involving 229 patients from 2009 to 2023, showed significant evidence that guaraná may help reduce cancer-related fatigue, despite variations in the studies included.
  • - The findings support guaraná's potential benefits, but more extensive randomized controlled trials are needed to confirm its effectiveness for treating cancer-related fatigue.
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Background: The cause of oropharyngeal dysphagia in patients with coronavirus disease (COVID-19) can be multifactorial and may underly limitations in swallowing rehabilitation.

Objective: Analyze the factors related to dysphagia in patients with COVID-19 immediately after orotracheal extubation and the factors that influence swallowing rehabilitation.

Design And Setting: A retrospective study.

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Background: Breast cancer is a public health problem with both high incidence and cure rates. After treatment, patients are monitored for long periods of time due to the risk of recurrence. Thus, staging and follow-up strategies should consider not only the best results for the patient but also its costs for the public health system.

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Objectives: A secular trend of earlier puberty has been observed in girls, and, although more uncertain in boys, is associated with an increasing trend in the prevalence of overweight and obesity. We aimed to compare the median ages of sexual maturation stages in schoolchildren from a city in southern Brazil over a 5-year period, according to weight status and type of school.

Methods: Two cross-sectional studies were performed in 2007 and 2012/2013, including 2215 and 1614 schoolchildren, respectively.

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This cross-sectional study uses data from the Brazilian Unified Health System to compare the number of hospital admissions for treatment of noncommunicable diseases from January to June 2020 with that during the corresponding period in each of the previous 3 years in São Paulo, Brazil.

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Brazilian law requires that treatment for breast cancer begin within 60 days of diagnosis. This waiting time is an indicator of accessibility to health services. The aim of this study was to analyze which factors are associated with waiting times between diagnosis and treatment of breast cancer in women in Brazil between 1998 and 2012.

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Emergency departments are facing an unprecedented challenge in dealing with patients who have coronavirus disease 2019 (COVID-19). The massive number of cases evolving to respiratory failure are leading to a rapid depletion of medical resources such as respiratory support equipment, which is more critical in low- and middle-income countries. In this context, any therapeutic and oxygenation support strategy that conserves medical resources should be welcomed.

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Introduction: Drug interaction is an important cause of global morbidity. It is of particular importance in cancer patients since they are often in use of polypharmacy, related to interactions between the drugs and the chemotherapeutics used.

Objective: To evaluate the drug interaction between chemotherapy and other drugs in cancer patients.

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Introduction: Peripheral neuropathy is a disorder that affects the cell body, axon or myelin of motor or peripheral sensory neurons and occurs in 60-100% of patients who are submitted to dialysis due to chronic kidney disease. Uremic neuropathy (UN) is attributed to the accumulation of organic waste, evident in patients with reduced glomerular filtration rate.

Objectives: This review aims to make clinical characteristics of uremic neuropathy evident enabling early diagnosis and treatment.

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Article Synopsis
  • Structural disparities within Brazil's public health system lead patients to migrate for better treatment options, resulting in overcrowded facilities in large centers.
  • A study conducted on 217 oncology patients revealed that about 10% had discrepancies in their registered addresses, with nearly 43% coming from other states, primarily seeking treatment.
  • The findings highlight an informal trend in healthcare migration, suggesting the need for reevaluation of public health policies due to its socio-economic impacts on both patients and the healthcare system.
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  • Male Breast Cancer (MBC) is rare, leading to limited understanding and treatment strategies based mainly on female cases; this study focuses on MBC mortality in Brazilian men from 2005 to 2015.
  • The research, using data from Brazil's Unified Health System, revealed 1,521 MBC-related deaths, with significant mortality variations across different regions and higher rates in older age groups.
  • Findings indicated that MBC mortality significantly increased during the decade studied, particularly among men aged 80 and older, suggesting a need for better awareness and targeted healthcare strategies.
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  • Early detection of breast cancer is crucial for lowering mortality rates, with primary health care playing a key role in Brazil's public health approach.
  • A study analyzed the relationship between breast cancer mortality and primary health care indicators across 5,700 Brazilian municipalities using 2010 data on women's deaths.
  • Findings suggested that higher primary care coverage correlated with increased breast cancer mortality, while better education and reduced income inequality were linked to lower mortality rates, highlighting the need for improved public health policies.
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Article Synopsis
  • * Findings showed a rise in hospitalizations for lower limb surgeries, which corresponded with an increase in deaths and a higher surgical mortality rate, particularly for hip procedures.
  • * Overall, there was a significant increase in elective nontraumatic orthopedic surgeries during the study period, leading to higher costs for Brazil's Unified Health System due to rising hospitalization demands.
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Objective: The present study analyzed the temporal trend of stroke mortality according to sex in individuals aged 15-49 years in the different regions of Brazil between 1997 and 2012.

Results: There was progressive reduction in mortality rate due to stroke in Brazil. The reduction trend was the same for both sexes, although mortality remained slightly higher among men.

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Article Synopsis
  • * The study analyzed mortality data from women over 50, revealing a 9% overall increase in age-adjusted OC mortality and significant rises in specific age groups: 28.4% for ages 50-54 and 25.1% for ages 75-79.
  • * Despite fluctuations in mortality rates during the study period, the overall trends indicate relative stability in OC mortality in Brazil.
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Fatigue is frequent among oncologic patients. Unpurified Paullinia cupana dry extract showed encouraging results for chemotherapy-induced fatigue in our previous studies. We report two randomized, double-blind studies with a standardized dry purified Paullinia cupana extract named PC-18.

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Oncology is an essential field of medicine; however, its teaching is occasionally underemphasized and uncoordinated during medical school. An alternative method of providing additional oncological information to medical students is through extracurricular activities, such as congresses and medical student associations. The aim of this paper is to describe a Medical Student Oncology Congress entirely designed and organized by medical students.

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