Evaluation of benazepril in cats with heart disease in a prospective, randomized, blinded, placebo-controlled clinical trial.

Background: Heart disease is an important cause of morbidity and mortality in cats, but there is limited evidence of the benefit of any medication.

Hypothesis: The angiotensin-converting enzyme inhibitor benazepril would delay the time to treatment failure in cats with heart disease of various etiologies.

Animals: One hundred fifty-one client-owned cats.

Comparison of hydroalcoholic rubbing and conventional chlorhexidine scrubbing for aseptic skin preparation in dogs.

Objective: To compare preparation time, ease of application, and elimination of skin contamination of 3 skin preparation methods for asepsis.

Study Design: Experimental study.

Animals: Healthy dogs (n = 6) with no clinical signs of skin disease.

Moving from information and collaboration to action: report from the 3rd International Dog Health Workshop, Paris in April 2017.

Background: Breed-related health problems in dogs have received increased focus over the last decade. Responsibility for causing and/or solving these problems has been variously directed towards dog breeders and kennel clubs, the veterinary profession, welfare scientists, owners, regulators, insurance companies and the media. In reality, all these stakeholders are likely to share some responsibility and optimal progress on resolving these challenges requires all key stakeholders to work together.

Evaluation of QT interval prolongation in dogs with heart failure.

Comparison of the QT interval and corrected QT interval values that were calculated by the methods of Bazett (QTc1) and Fridericia (QTc2) were made between dogs with or without cardiac diseases to determine the influence of the QT interval on canine heart failure. Upon comparison of the measured values on ECG between the cardiac disease and non-cardiac disease groups, it was observed that the heart rate(HR) was significantly higher in the cardiac disease group than in the non-cardiac disease group, although the QT interval was similar in the two groups. The QTc1 and QTc2 were significantly longer in the cardiac disease group than in the non-cardiac disease group.

Long-term tolerability of benazepril in dogs with congestive heart failure.

Objectives: To test the tolerability of long-term administration of benazepril in dogs with congestive heart failure (CHF).

Methods: The study was a prospective, randomized, double-blinded, placebo-controlled clinical trial. A total of 162 dogs with New York Heart Association (NYHA) class II-IV heart failure caused by chronic valvular disease (CVD) or dilated cardiomyopathy (DCM) were enrolled.