Publications by authors named "Jean Doyle"
Article Synopsis
- Accelerated bone loss is common in the first 2-3 years after traumatic spinal cord injury (TSCI), especially in the distal femur and proximal tibia, with limited studies focused on treating this condition.
- A study conducted from 2018 to 2023 involved two groups: an 'acute interventional cohort' receiving zoledronic acid (ZOL) and a 'chronic non-interventional cohort' not receiving treatment, both monitored for bone mineral density (BMD) over time.
- Results showed that the acute group, despite receiving ZOL, experienced significant BMD decline at 12 and 48 months, indicating that this treatment did not effectively prevent bone loss, highlighting the need for further research on
Atypical femur fractures (AFF) are a rare but serious complication of long-term bisphosphonate use. Although clearly defined by ASBMR criteria, a proportion of patients with AFFs may go unrecognized and the use of qualitative fracture criteria may lead to uncertainty in AFF diagnosis, with significant therapeutic implications. A score that rapidly and accurately identifies AFFs among subtrochanteric femur fractures using quantitative, measurable parameters is needed.
View Article and Find Full Text PDFBackground: Low bone mineral density (BMD) is a known independent predictor of mortality in the general elderly population. However, studies in patients with end-stage renal disease (ESRD) are limited. The present study evaluated mortality during long-term follow-up in a population of patients having dialysis for ESRD, in whom BMD was also measured.
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