Publications by authors named "Jean Christophe Maurin"

Introduction: Access cavity preparation is a crucial step in root canal treatment but is one of the most complex procedures in the curriculum to learn, with students often reporting spatial orientation difficulties during drilling. The present study aimed to evaluate the influence of spatial abilities on the preparation of endodontic access cavities among third-year dental students.

Materials And Methods: Students from Lyon dental faculty participated voluntarily.

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Access to dental care in Cameroon is a public health issue, particularly for children living in rural areas. Given the lack of recent data, the investigation of children's oral health along with their oral hygiene behavior, needs in terms of care, and access to oral hygiene materials were investigated. This cross-sectional pilot study was conducted in Bamendou, Western Region of Cameroon.

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Objectives: The aim of this study was to evaluate the capacity of an intra-oral scanner (IOS) to assess the position of an endodontic guide in vitro.

Methods: Fourteen extracted human teeth were placed into a maxillary model and scanned using computed tomography and a reference laboratory scanner. An ideal endodontic guide was then created and modified by adding defects of different thicknesses to simulate incorrect positions: 50 μm, 150 μm, 400 μm, and 1000 μm.

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Background: Many causes of resorption remain unclear and are thus identified as idiopathic. In such cases, management is difficult, especially when multiple teeth are involved. The aim of the present study was to assess the literature regarding the medical, clinical, and radiographic aspects of multiple idiopathic resorptions (MIR) and to examine the factors associated with the risk of extraction.

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Background: The present study aimed to classify the relative contributions of four biomechanical factors-the root-end filling , the apical , the root , and the -on the root stresses of the resected premolar.

Methods: A design of experiments approach based on a defined subset of factor combinations was conducted to calculate the influence of each factor and their interactions. Sixteen finite element models were created and analyzed using the von Mises stress criterion.

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In recent years, additive manufacturing (AM) technologies have attracted significant interest in many industrial and research fields, particularly in tissue engineering. Printed structures used as physical and bioactive supports for tissue regeneration are becoming increasingly complex so as to mimic natural tissues in order to answer future medical needs. Reproducing the biological environment of a native tissue from the microscopic to the macroscopic scale appears to be the best strategy for effective regeneration.

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Due to their osteoconductive and osteoinductive abilities, bioglasses (BGs) have attracted attention in tissue engineering, especially for mineralized tissue. The aim of this study is to review the current state of the art on the effects of BGs produced by sol-gel on cells for dental and periodontal regeneration. The study also discusses associated antibacterial properties.

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Phosphate-based glasses have been attracting attention due to their possible medical applications arising from unique dissolution characteristics in the human body leading to the possibility of new tissue regeneration. In this study, the leaching kinetics of a series of melt-quenched Sr-doped phosphate glasses are presented. Regardless of the presence of Sr, all the glasses have an initial linear and sustained release of the ions followed by a plateau.

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Objectives: A scoping review was conducted to explore the use of FDI criteria 10 years after their introduction. The first aim was to compare the amount of studies using the FDI and/or the modified USPHS criteria. The second aim was to analyse the use of the FDI criteria in clinical trials evaluating direct dental restorations.

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Dentinal sensitivity is a clinical condition daily encountered by practitioners and constitutes the symptoms of dentinal hypersensitivity, a common dental pain affecting on average 30% of the population. However, the management of this pathology is not always effective due to the lack of knowledge particularly concerning the means by which dental nociceptive signals are transduced. The mechanisms underlying dentin sensitivity still remain unclear probably due to the structural and functional complexity of the players including odontoblasts, nerve endings and dentinal fluid running in the dentinal tubules.

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Dental pain arises from exposed dentin following bacterial, chemical, or mechanical erosion of enamel and/or recession of gingiva. Thus, dentin tissue and more specifically patent dentinal tubules represent the first structure involved in dentin sensitivity. Interestingly, the architecture of dentin could allow for the transfer of information to the underlying dental pulp via odontoblasts (dentin-forming cells), via their apical extension bathed in the dentinal fluid running in the tubules, or via a dense network of trigeminal sensory axons intimately related to odontoblasts.

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Article Synopsis
  • - MAP-1B is a microtubule-associated protein crucial for stabilizing microtubules during the development of nerve cells, particularly in odontoblasts involved in tooth formation, and its expression is regulated by FMRP.
  • - The study employed various methods like real-time PCR and immunochemistry to analyze MAP-1B expression, discovering it in adult and embryonic human dentin-forming cells, especially in response to differentiation states.
  • - Findings suggest that MAP-1B plays a significant role in the terminal differentiation of odontoblasts, alongside other proteins like MAP2 and tau, indicating its importance in both healthy development and dental conditions.
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Odontoblasts are organized as a single layer of specialized cells responsible for dentine formation and presumably for playing a role in tooth pain transmission. Each cell has an extension running into a dentinal tubule and bathing in the dentinal fluid. A dense network of sensory unmyelinated nerve fibers surrounds the cell bodies and processes.

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Article Synopsis
  • Odontoblasts are cells that create dentin in teeth and may also play a role in tooth pain, but this function has not been definitively proven before.
  • New research shows that human odontoblasts can generate electrical signals and action potentials, indicating they have excitability similar to nerve cells.
  • The study finds that odontoblasts have specific sodium channel subunits which cluster with nerve fibers, suggesting they could act as sensor cells involved in transmitting tooth pain signals.
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Purpose: The aim of this study was to compare the bond strengths of two new self-etching one-step (Prompt L-Pop 2 and Adper Prompt L-pop) to a total-etch three-step dentin bonding system (Scotchbond Multipurpose Plus).

Materials And Methods: One hundred twenty human molars were randomly divided into 3 groups of 40 specimens each. Dentin surfaces of each group were bonded with either Scotchbond Multipurpose Plus (SMP), a three-step system, Prompt L-Pop 2 (PLP), or Adper Prompt L-Pop (APLP), two one-step bonding systems--according to manufacturers' recommendations.

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Semaphorin 7A (SEMA 7A) is a membrane-anchored member of the semaphorin family of guidance proteins, previously identified in the immune system. Expressed in central and peripheral nervous system during embryonic and post-natal stages, it can mediate neuronal functions by promoting axonal growth. We show here that SEMA 7A is expressed in human odontoblasts in vivo and in vitro and that its expression is correlated with the establishment of dentin-pulp complex terminal innervation .

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Reelin is a large extracellular matrix (ECM) glycoprotein strongly expressed during embryonic development in the central nervous system and involved in architectonic brain development. It could participate in axon plasticity processes or adhesion-recognition between nerve fibers in adulthood. Previously identified from a subtractive cDNA library of fully differentiated human odontoblasts, reelin might be involved in the relationship between dental nerves and odontoblasts in as so far the latter are in close association with pulpal nerve fibers.

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Synopsis of recent research by authors named "Jean Christophe Maurin"

  • - Jean Christophe Maurin's recent research focuses on various aspects of dental education and oral health, emphasizing the importance of spatial abilities in endodontic procedures and the state of oral health among rural children in Cameroon.
  • - His studies highlight the challenges dental students face with spatial orientation during access cavity preparations, alongside addressing pressing public health issues regarding children's access to dental care in underprivileged areas.
  • - Additionally, Maurin's work incorporates technological advancements in dentistry, such as the use of intra-oral scanners for guide fitting and systematic reviews on the clinical management of various dental conditions, demonstrating a commitment to improving both educational practices and patient outcomes in dental health.