Synopsis of recent research by authors named "Jean C-Y Tien"
- Jean C-Y Tien's research primarily focuses on the role of nuclear receptors and long noncoding RNAs in the progression of prostate and breast cancers, highlighting the intricate molecular mechanisms involved in tumor development and metastasis.
- In a notable study, Tien identified ARLNC1 as a critical androgen receptor-regulated long noncoding RNA that enhances androgen receptor signaling and contributes to prostate cancer advancement.
- Another significant finding indicates that the transcriptional coactivator SRC-3 is essential for the development of castration-resistant prostate cancer, suggesting potential therapeutic targets for advanced prostate cancer management.