Toluene inhalation exposure for 13 weeks causes persistent changes in electroretinograms of Long-Evans rats.

Studies of humans chronically exposed to volatile organic solvents have reported impaired visual functions, including low contrast sensitivity and reduced color discrimination. These reports, however, lacked confirmation from controlled laboratory experiments. To address this question experimentally, we examined visual function by recording visual evoked potentials (VEP) and/or electroretinograms (ERG) from four sets of rats exposed repeatedly to toluene.

Effect of cataract and its removal on signal strength and peripapillary retinal nerve fiber layer optical coherence tomography measurements.

Purpose: To assess the effect of cataract on optical coherence tomography (OCT), signal strength (SS), and peripapillary retinal nerve fiber layer (RNFL) thickness measurements.

Methods: Peripapillary RNFL thickness measurements were obtained by Stratus OCT scans using the Fast RNFL thickness (3.4) acquisition protocol before and after cataract extraction in 45 patients with cataract, including 23 glaucoma patients.