Publications by authors named "Jean Bosco Surwumwe"
Article Synopsis
- * In a cohort of 51 CRC patients from Rwanda, TP53 variants were found in 45.1% of cases, primarily of the missense type, with notable mutations including c.455dup, c.524G>A, and c.733G>A, and a predominance of specific mutation sequences.
- * The study also revealed that most TP53 mutations were associated with the CMS2 subtype, suggesting that these variants may play a significant role in the development of this
Background: Gastric cancer is the sixth most frequently diagnosed cancer and third in causing cancer-related death globally. The most frequently mutated gene in human cancers is TP53, which plays a pivotal role in cancer initiation and progression. In Africa, particularly in Rwanda, data on TP53 mutations are lacking.
View Article and Find Full Text PDFObjective: The shortage of pathologists is a worldwide problem that is more severe in Africa. One of the solutions is the use of telepathology (TP); however, most of the TP systems are expensive and unaffordable in many developing countries. At the University Teaching Hospital of Kigali, Rwanda, we assessed the possibility of combining commonly available laboratory tools into a system that can be used for diagnostic TP using Vsee videoconferencing.
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