Publications by authors named "Jean Baptiste Pretalli"
Vulvar Paget's disease: A population-based cancer registry descriptive study.
J Gynecol Obstet Hum Reprod
December 2024
Article Synopsis
- Vulvar Paget's Disease (VPD) is a rare skin cancer with good outcomes but high recurrence rates, affecting patients' quality of life.
- A study conducted in Franche Comté examined data from 21 patients diagnosed with VPD over 40 years, revealing that many experienced a delayed diagnosis and had a significant likelihood of recurrence, especially after surgical treatment.
- The use of postoperative adjuvant therapies notably improved patients' chances of remaining free from recurrence, highlighting the importance of thorough follow-up care.
Article Synopsis
- Acute respiratory failure is a serious condition often treated in emergency departments, where high-flow nasal oxygen (HFNO) is becoming a popular treatment option for patients experiencing it.
- The study aims to compare the effectiveness of HFNO versus conventional oxygen therapy within the first hour of emergency treatment, hypothesizing that HFNO will lead to fewer patients needing further ventilatory support.
- This trial involves 500 patients and is approved by ethical boards, with plans for results dissemination in peer-reviewed journals and conferences.
Introduction: Terrorist threats are a worldwide phenomenon. The injuries caused with military weapons or explosives are multiple and unusual for civilian care services. Damage control (DC) training has then become a critical need.
View Article and Find Full Text PDFBackground: Shiga toxin-associated hemolytic uremic syndrome (STECHUS) is the main cause of acute kidney injury in children and may be responsible for adverse outcomes despite an apparent quiescent period.
Objective: To describe the medium- and long-term kidney outcomes of pediatric STECHUS in a French region.
Methods: A single-center, descriptive, retrospective study of STECHUS cases that occurred at Besançon University Hospital between 1999 and 2017 in children up to 17 years of age was conducted.
Article Synopsis
- Diagnosing acute heart failure (AHF) in elderly patients with acute dyspnea is challenging, prompting the study of various biomarkers for improved accuracy.
- A multicenter study in France assessed the effectiveness of five biomarkers (NT-proBNP, hs-cTnI, ST2, galectin-3, CD146) in diagnosing AHF among 238 elderly patients over a four-year period.
- While individual biomarker accuracies varied, NT-proBNP alone provided the best diagnostic accuracy (0.72), and combining the biomarkers did not significantly improve upon this.
Article Synopsis
- Management of first episodes of primary spontaneous pneumothorax (air in the chest cavity) is debated, with this study comparing simple aspiration and chest tube drainage as treatment methods.
- The trial involved 402 adults aged 18-50 and measured lung expansion 24 hours post-treatment, finding a higher failure rate in the aspiration group (29%) compared to the chest tube group (18%).
- Despite higher failure rates, the aspiration method resulted in less overall pain and fewer complications, with recurrence rates of pneumothorax being 20% for aspiration and 27% for drainage.
Introduction: Weight status perception (WSP) is the subjective assessment of one's own body weight. It is not correlated with the body mass index (BMI). People practicing sports, including overweight people, tend to perceive themselves as normal weight.
View Article and Find Full Text PDFBackground: Noise levels are monitored in call centres. A maximum of 52 to 55 dB(A) is recommended in order to prevent adverse events. We aimed at assessing the noise level and the impact of a visual noise indicator on the ambient noise level in a French Regional Emergency Medical Dispatch Centre (EMDC).
View Article and Find Full Text PDFProne Positioning for Severe Acute Respiratory Distress Syndrome in COVID-19 Patients by a Dedicated Team: A Safe and Pragmatic Reallocation of Medical and Surgical Work Force in Response to the Outbreak.
Ann Surg
December 2020
Objective: The aim of this study was to define whether rapidly reallocating health care workers not experienced with PP for performing PP in ICU is feasible and safe.
Summary Background Data: In the setting of severe acute respiratory distress syndrome (ARDS), the use of prone and supine positioning procedures (PP) has been associated with improved oxygenation resulting in decreased mortality. Nevertheless, applying PP is time consuming for ICU staffs that are at risk of mental of physical exhaustion, especially with the constant surge of admitted COVID-19 patients with severe ARDS.
Background: Sterility is a major late effect of radiotherapy and chemotherapy treatments. Iatrogenic sterility is often permanent and greatly impacts long-term quality of life. Ovarian tissue cryopreservation (OTC) performed before gonadotoxic treatments with subsequent autograft is a method of fertility preservation available for girls and women.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates the link between air pollution and primary spontaneous pneumothorax (PSP), a type of lung condition, aiming to provide clearer insights than previous research.
- It utilizes a case-crossover design, analyzing data from 948 subjects over four years in French emergency departments, while considering various pollutants like nitrogen dioxide, ozone, and particulate matter.
- The results indicate no significant difference in exposure to these pollutants between patients with PSP and controls, although the possibility of an association with higher levels of ozone exposure remains uncertain.
Aims: Several variables are able to influence the antidepressant effects of repetitive transcranial magnetic stimulation (rTMS), particularly the intensity of stimulation, which is generally expressed according to the resting motor threshold (RMT). The aim of our study was to investigate whether or not RMT changes during the treatment of resistant depression by rTMS and whether these fluctuations could alter treatment outcome.
Methods: Seventy-five inpatients suffering from unipolar or bipolar treatment-resistant depression and who had been antidepressant-free or taking a stable antidepressant drug and a daily dose of benzodiazepine for at least a month received a left prefrontal rTMS session once a day for 10 days at 10 Hz and 95% RMT.