Publications by authors named "Jean B Delobel"
Article Synopsis
- VIPomas are rare tumors that cause life-threatening hormonal issues by secreting vasoactive intestinal peptide (VIP), and plasma VIP can be measured to confirm diagnosis, although interference in tests can occur.
- Researchers developed three methods to detect potential interference in VIP radioimmunoassay (RIA) tests and studied both patients suspected of false positive VIP results and those with confirmed VIPomas.
- Their results showed that all false positive patients had interference in the tests, whereas no such issues were found in confirmed VIPoma patients, indicating the importance of using their developed techniques when test results don't match clinical symptoms.
Random forests to predict rectal toxicity following prostate cancer radiation therapy.
Int J Radiat Oncol Biol Phys
August 2014
Purpose: To propose a random forest normal tissue complication probability (RF-NTCP) model to predict late rectal toxicity following prostate cancer radiation therapy, and to compare its performance to that of classic NTCP models.
Methods And Materials: Clinical data and dose-volume histograms (DVH) were collected from 261 patients who received 3-dimensional conformal radiation therapy for prostate cancer with at least 5 years of follow-up. The series was split 1000 times into training and validation cohorts.