Publications by authors named "Jeahyeon Cho"
Neuropharmacology
May 2017
Article Synopsis
- Dopamine (DA) is crucial for voluntary movement, and a lack of DAergic neurons can cause movement disorders.
- The study investigated the neuroprotective effects of lisuride, a DA D2-like receptor agonist, and found it preserved tyrosine hydroxylase (TH) levels in a mouse model and neuronal cultures exposed to 6-hydroxydopamine (6-OHDA).
- The neuroprotective effects of lisuride are primarily mediated by the DA D3 receptor, as inhibiting this receptor blocked the protective action, particularly against mitochondrial damage in DAergic neurons.
