Publications by authors named "Jcg Morales"

Article Synopsis
  • The Neuroform Atlas Stent System is a new hybrid device designed for treating unruptured aneurysms, combining elements of both open and closed cell stents.
  • A study involving 30 patients showed the stents were successfully delivered and positioned in 29 cases, with most aneurysms demonstrating significant improvement post-treatment.
  • The Atlas stent is safe and easy to implant with fewer complications compared to other stents, but its low thrombogenic potential may result in incomplete aneurysm occlusion over time.
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Glioblastomas (GBs) are the most common and lethal primary brain tumors in the adults. Glioblastomas originates either from astrocytes that have accumulated mutations and de-differentiated or from neural stem cells within the subventricular zone (SVZ) in close contact with the vasculature. Recently, several studies have hypothesized that gliomagenesis occurs in perivascular niches with highly invasive peripheral proliferating zones.

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Glioblastoma multiforme (GBM), a highly aggressive brain cancer characterized by uncontrolled proliferation, resistance to cell death, angiogenesis, and vascular edema, remains one of the deadliest types of cancer. The subventricular zone (SVZ) harbors cells with great proliferative potential, and the microenvironment within the SVZ is permissive to growth and proliferation. This neurogenic niche is suspected to be a vulnerable site for the origin of subtypes of GBM.

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