Publications by authors named "Jazz Cagan"
Article Synopsis
- SARS-CoV-2 can spread from asymptomatic individuals, posing a greater risk to cancer patients who frequently visit healthcare facilities and are more vulnerable to severe COVID-19 outcomes.* -
- A study of lung cancer patients revealed that over half of those with evidence of SARS-CoV-2 infection were asymptomatic at diagnosis, and a significant number were never clinically diagnosed.* -
- The findings indicate that older patients and those with early-stage lung cancer are more likely to have asymptomatic infections, highlighting the need for continued preventive measures in high-risk populations.*
Article Synopsis
- * A longitudinal study involving 296 LC patients (median age 69) collected blood samples every three months, analyzing the effects of both time-independent and time-dependent variables on SAb levels using a regression model.
- * Key findings revealed that prior SARS-CoV-2 infections and booster vaccinations significantly increased antibody titers, while chemotherapy and steroid use led to decreased levels; additionally, female patients with a history of smoking showed significantly lower titers.
Patients diagnosed with lung cancer (LC) exhibit increased susceptibility to SARS-CoV-2 infection. Rodilla et al. monitor the levels of plasma anti-nucleocapsid antibodies within a cohort of fully vaccinated LC patients and reveal that the actual infection rate is nearly twice the documented rate, indicating a significant prevalence of unreported cases.
View Article and Find Full Text PDFIn comparison to the general population, lung cancer patients are more likely to suffer from severe Coronavirus disease (COVID-19) and associated mortality. Considering this increased risk, and in order to prevent symptoms and severe disease, patients with lung cancer have been prioritized for COVID-19 vaccination primary and booster doses. Despite this, the pivotal clinical trials did not include these patients, which leaves open questions regarding vaccine efficacy and humoral immune response.
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