Publications by authors named "Jayusman A"
Article Synopsis
- Most patients with advanced non-small cell lung cancer (NSCLC) have a poor survival rate, and the study investigates how nutritional status impacts treatment response and overall survival in these patients.
- The study followed 174 patients with stage II-IV NSCLC over two years, revealing that only a small percentage achieved a complete response to treatment, and the median survival was 12 months.
- Findings indicated that being male and overweight or obese are linked to lower survival rates, regardless of other factors like age, disease stage, and baseline health.
Article Synopsis
- - Lung cancer is a leading cause of cancer-related deaths among men, necessitating a biological marker for better treatment outcomes in non-small cell lung cancer (NSCLC) patients, particularly in Indonesia.
- - A retrospective cohort study analyzed various blood test results (e.g., hemoglobin, leukocytes, tumor markers) to assess their impact on the survival rate of NSCLC patients.
- - Significant findings indicated that poor prognostic factors include advanced performance status, late TNM stage, high white blood cell counts, low platelets, and other lab abnormalities, with the need for more research on their correlatives.
Objective: This study aims to evaluate the correlation between electrolytes and serial miRNAs from our previous study. We want to prove that there is the molecular basis that underlying electrolytes disturbances as the predictive indicator to the outcome in NSCLC patients.
Results: There were positive correlation between potassium level with miR-34 (p = 0.
Preparing for the Next Pandemic: An Asian National Cancer Centers Alliance (ANCCA) Initiative.
Asian Pac J Cancer Prev
September 2021
The COVID-pandemic has shown significant impact on cancer care from early detection, management plan to clinical outcomes of cancer patients. The Asian National Cancer Centres Alliance (ANCCA) has put together the 9 "Ps" as guidelines for cancer programs to better prepare for the next pandemic. The 9 "Ps" are Priority, Protocols and Processes, Patients, People, Personal Protective Equipments (PPEs), Pharmaceuticals, Places, Preparedness, and Politics.
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- This study investigates the potential of the FIB-4 index as a predictor of mortality in patients with both hematological malignancies and COVID-19, focusing on finding an optimal cut-off value.
- Conducted at Dharmais National Cancer Hospital in Indonesia, it analyzed 70 patients and found a significant correlation between higher FIB-4 values and increased mortality risk over a 3-month period.
- The results indicated that a FIB-4 index greater than 3.85 had strong predictive power for mortality, with implications for patient management and treatment decisions.
Objective: This study aimed to compare the mortality rate between advanced-stage non-small cell lung cancer patients (NSCLC) with and without COVID-19. This study also explores the possible laboratory characteristics used for prognostication in patients with NSCLC and COVID-19. Additionally, this study evaluated potential differences in laboratory values between the case and control groups.
View Article and Find Full Text PDFAcrylamide (AA) is a carcinogenic substance found in food, cigarette smoke and in an environment exposed to acrylamide. This study aims to analyze AA levels in dried blood spot (DBS) samples of lung cancer patients with smoking record, without smoking record, and also in the negative blank. Analysis of AA levels was determined by liquid chromatography tandem mass spectrometry (LC-MS/MS) and DBS extraction using protein precipitation techniques.
View Article and Find Full Text PDFBackground: Lung cancer is the most common cause of death in men in the world and in Indonesia where non-small cell carcinoma lung cancer (NSCLC) constitutes 85% of all lung cancer cases. The high mortality rate is due to a poor prognosis and is often diagnosed as having advanced stages. If it is known at the initial stage, the prognosis of lung cancer will be better.
View Article and Find Full Text PDFObjectives: To improve the quality of invasive pulmonary aspergillosis (IPA) management for intensive care unit (ICU) patients using a practical diagnostic scoring model.
Methods: This nested case-control study aimed to determine the incidence of IPA in 405 ICU patients, between July 2012 and June 2014, at 6 hospitals in Jakarta, Indonesia. Phenotypic identifications and galactomannan (GM) tests of sera and lung excreta were performed in mycology laboratory, Parasitology Department, Faculty of Medicine, Universitas Indonesia in Jakarta, Indonesia.
Nineteen patients with stage III & IV nonsmall cell lung cancer were treated with a regimen containing paclitaxel and carboplatin at Dharmais National Cancer Center Hospital and Pertamina Central General Hospital, Jakarta, Indonesia. There were 14 males and 5 females, the histologic diagnosis being adenocarcinoma in 13 patients, squamous carcinoma in 5 patients and adenosquamous carcinoma in 1 patient. Fourteen patients were in stage IV, 4 had stage IIIB, and one had stage IIIA disease.
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