Toxicity profile of standardized Krishna Vajra Abhraka bhasma made from biotite mica.

Introduction: The Bhasmas, herbo-minerals, are reported to produce adverse effects when used clinically. Therefore, the present study aimed to assess the safety of Krishna Vajra Abhraka Bhasma (KVB), through acute and subacute toxicity testing.

Materials And Methods: After ethics committee approval, total 66 Wistar albino rats weighing 180-200 gms were used.

Anti-inflammatory and Analgesic Activities of Topical Formulations of Powder in Rat Model of Chronic Inflammation.

Introduction: The incidence of arthritis is quite high and there is a need for the search of natural products to halt the progression of disease or provide symptomatic relief without significant adverse effects.

Aim: This study aimed at evaluating the anti-inflammatory and analgesic activities of topical in an animal model of chronic inflammation.

Materials And Methods: Albino rats of either sex were divided into five groups of six rats each (Group I - Control, Group II -Gel base, Group III - paste, Group IV - gel, Group V- Diclofenac gel).

Evaluation of Effect of Nishamalaki on STZ and HFHF Diet Induced Diabetic Neuropathy in Wistar Rats.

Introduction: Diabetic neuropathy is one of the most common complications affecting 50% of diabetic patients. Neuropathic pain is the most difficult types of pain to treat. There is no specific treatment for neuropathy.

Preventive and Protective Effect of Nishamalaki in STZ Induced Diabetic Complications in Wistar Rats.

Introduction: Diabetes is a metabolic disease of vital health importance because of the complications associated with it. Clinical trials and animal studies have demonstrated the anti-hyperglycaemic effect of Nishamalaki. Present study was planned to evaluate the protective potential of Nishamalaki on diabetic complication in rats.

Anti-nociceptive Effect of Entada Phaseoloides Seeds Formulation after Topical Application in Arthritic Wistar Rats.

Objectives: To study the effect of topical application of different formulations of Entada phaseoloides seeds for analgesic activity in arthritic wistar rats.

Material And Methods: EP (Entada Phaseoloides) seeds were powdered after removing the shell. Paste was prepared by adding water and ointment with polyethylene glycol (PEG 400) & Carbowax 3350.

Understanding redox homeostasis and its role in cancer.

When a cell is damaged or altered without repair to its system, it usually dies. But if such damaged or unrepaired cells do not die and proliferate with uncontrolled growth; a mass of cancer cells develop. Cancer has a complex aetiology with multiple risk factors that involve the interplay between genetic and environmental influences.

Hepatorenal repercussions of alcoholic exposure in a rat model: a dose-dependent study of metformin intervention.

Background: Diabetes mellitus is an alarming life style disease in the modern world. Exploitation of the anti-diabetic drugs for the amelioration of diabetes and associated life style diseases has become an imperative concern. In this milieu, this study was designed to explore the plausible effects of metformin intervention on hepatic and renal functions in a rat model of alcoholic liver disease.