Endocrine and Metabolic Profile of Different Phenotypes of Polycystic Ovarian Syndrome.

Background: Polycystic ovarian syndrome (PCOS) is a common endocrinopathy associated with wide heterogeneity and serious clinical implications. Prevalence and characteristics of different phenotypes are not well defined. Therefore, this study was planned to determine the prevalence of four phenotypes of PCOS and to evaluate their endocrine and metabolic parameters including insulin resistance and metabolic syndrome with respect to controls.

Preanalytical error occurrence rate in clinical chemistry laboratory of a public hospital in India.

Background: The pre and post analytical phase in a testing cycle contributes up to 93% of total laboratory errors. Hence, it is of utter importance for the laboratory to study error occurrence rates during the testing cycle and implement a quality improvement plan to release an accurate result.

Methods: The present study was conducted during the period 2008 - 2009 in the clinical biochemistry lab in Lady Hardinge Medical College and associated hospitals.

Basal core promoter, precore region mutations of HBV and their association with e antigen, genotype, and severity of liver disease in patients with chronic hepatitis B in India.

Spontaneous mutations of hepatitis B virus (HBV) could influence the severity of liver disease. Since the basal core promoter (BCP) and the precore (Pc) regions are important for viral replication, these regions were examined for naturally occurring mutations and were correlated with the genotype, e antigen status, and severity of liver disease. In 82 patients with histologically confirmed chronic hepatitis B, the BCP and Pc regions were sequenced and aligned with known wild-type sequences.

Effect of esmolol on oxidant status and antioxidant activity in acute myocardial infarction.

Aims And Objectives: The role of oxygen free radicals in reperfusion injury to the heart in myocardial infarction (MI) has been postulated. In this study, the clinical and antioxidant effects of esmolol, an ultra-short acting beta blocker in patients of acute MI was studied.

Material And Methods: This was a randomized, double-blind, controlled, prospective study.