Publications by authors named "Jaynee Vugts"
Background: Liver transplantation (LT) has been performed in a select group of patients presenting with unresectable or primary sclerosing cholangitis (PSC)-associated perihilar cholangiocarcinoma (pCCA) in the Mayo Clinic with a reported 5-year overall survival (OS) of 53% on intention-to-treat analysis. The objective of this study was to estimate eligibility for LT in a cohort of pCCA patients in two tertiary referral centers.
Methods: Patients diagnosed with pCCA between 2002 and 2014 were included from two tertiary referral centers in the Netherlands.
Background: Patients with resectable perihilar cholangiocarcinoma (PHC) on imaging have a substantial risk of metastatic or locally advanced disease, incomplete (R1) resection, and 90-day mortality. Our aim was to develop a preoperative prognostic model to predict surgical success, defined as a complete (R0) resection without 90-day mortality, in patients with resectable PHC on imaging.
Study Design: Patients with PHC who underwent exploratory laparotomy in three tertiary referral centers were identified.
Article Synopsis
- Low skeletal muscle mass is linked to poorer outcomes after surgery for perihilar cholangiocarcinoma (PHC), and this study aimed to assess the impact of muscle mass and density on overall survival (OS) in PHC patients.
- Data from 233 patients diagnosed with PHC between 2002 and 2014 were analyzed, comparing OS based on muscle mass and density measured via CT scans.
- The results indicated that while low skeletal muscle mass did not significantly affect OS, low muscle density was associated with a higher risk of early death within the first 6 months after diagnosis.
Background: Although several classifications of perihilar cholangiocarcinoma (PHC) include vascular involvement, its prognostic value has not been investigated. Our aim was to assess the prognostic value of unilateral and main/bilateral involvement of the portal vein (PV) and hepatic artery (HA) on imaging in patients with PHC.
Methods: All patients with PHC between 2002 and 2014 were included regardless of stage or management.
Background: Conditional survival is the life expectancy from a point in time for a patient who has survived a specific period after presentation. The aim of the study was to estimate conditional survival for patients with unresectable perihilar cholangiocarcinoma.
Methods: Patients with unresectable perihilar cholangiocarcinoma from two academic hospitals in the Netherlands between 2002 and 2012 were assessed.